Search: #Zoology
this week an ai formalized fermat's last theorem in 30 hours and another one got its yang-mills construction signed off by a nobel laureate's committee
biology is next hehe
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Ellie Dossantos is a talented midfielder for the Florida Southern College Moccasins. Originally from Northport, New York, Ellie attended Saint Anthony's High School, where she earned All-League honors in 2023 and 2024 and was named team captain in her senior season. She also earned First Team All-State recognition and helped her high school capture state and league championships.
In 2025, she appeared in all 18 games as a freshman, recording two assists. She continued making an impact in 2026, contributing goals and assists while becoming an important part of the midfield.
She is majoring in Biology and plans to pursue a career in dentistry.
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Do they not realize that what is making the biology community incensed by Ai marketers is the baseless timelines more than anything? Can Ai help find cures? YES. Will it magically do that in 5yrs? Absolutely not. Biology has no first principles
YOU NEED TO MAKE DATA FIRST FFS.
Papers finding no or only marginal differences between patients with LC and recovered controls are going to dominate the literature in the coming years - not because this is the truth but because this bullshit dogma needs to be pushed and accepted.
You can see that some docs are waking up - and catching on - the establishment now needs to double down - they need to prove "biological-clinical dissociation".
Papers such as this one are written to do exactly that. They don't further the field, help patients, or add scientific findings of use. That is not their purpose. Their purpose is to invalidate LC as a condition worthy of research/treatment.
Just look at this phrase in the abstract "biological-clinical dissociation" - what they mean by this is that the biology shows no evidence of the symptoms or dysfunctions being claimed.
subclinical = not important, not out of range enough to be important
I am so disgusted.
Share Dario’s optimism. AI is changing the pace of medical progress, and in our industry time is life. Already seeing this across @Pfizer from discovery to manufacturing.
But as a scientist I also know how humbling biology can be. Identifying a promising molecule is just the beginning. The only way to know if a medicine is safe and effective is careful, rigorous testing in patients. That takes time, and needs experienced researchers and physicians in the loop.
The future I see is AI’s speed and scientific discipline working together. If we get that right, patients will benefit sooner than many expect.
Medical knowledge is not advanced by studies that don’t study medical evidence. Studies are accepted into journals or rejected based on paradigm rather than evidence. It’s a mess.
A classic in the genre of medical disinformation. 👇
A new JAMA study uses surveys to assess regret among those who received hormones as teens.
42.5% did not return the surveys.
The authors nevertheless conclude that regret was “rare,” without acknowledging the 42.5% non-response in the limitations, and their conclusion is that gender Rx should not be restricted for youth (a non-sequitur). JAMA, apparently, sees this as worthy of publication.
The Washington Post (@washingtonpost) then uncritically reports the new study’s findings, also without any mention of the 42.5%.
This study will almost certainly be citation laundered, cited again and again in medical literature, media coverage, and legislative hearings, until its “findings” become “well-established truth.”
#HalefKöklerinÇağrısı #Yilser
Yildiz couldn’t even have a child from the man she loves or continue on her own legacy but that disgusting women can. The main couple is not going to even have a child biology child of theirs but a third party’s.
@ercanugur you’re literally trash
Creation fairytale is anti-White. It shits on decades of hard, careful work by European men who actually studied the world instead of inventing a Middle Eastern bedtime story.
Darwin and Wallace spent years observing, collecting, and reasoning their way to natural selection. Mendel’s careful pea experiments gave us the laws of inheritance. Malthus laid out the population pressure that drives the struggle for existence. Even Lamarck’s earlier attempts (flawed mechanism, honest effort) were part of the long European push to understand life through evidence instead of myth.
Those men built the foundations of modern biology, genetics, and evolutionary science. The creation story demands you throw all of it out because an ancient text says magic happened in six days and a talking snake handed out "forbidden" knowledge ( shout out to our Valkyrie @B_a_r_o_n___ for calling this out) No observations. No experiments. No rigor. Just “believe or else.”
That’s not piety. It’s sabotage of our folk’s actual intellectual achievements. European science gave the world the tools to understand how life really works. Bronze Age fairytales demand we unlearn them. Reject the myth that treats White scientific progress as an obstacle to faith.
There’s this my neighbor’s daughter that took Jamb last year and did so well. She performed well in Unilorin Post UTME too but didn’t gain admission.
She took Jamb again this year and repeated the whole process this year. She still passed, but instead of Pharmacy, she was given Plant Biology.
When the Mom told me about it, I wanted to tell her to tell the girl to reject it and better wait til next year, but she’d even paid School fee and started lectures already.
The Mom said it’s better than sitting at home wasting another year. In my head, when she graduates, you would wish she had wasted a year than wasting 4 years. I told her to take another Jamb form next year and try again. She’s still a young girl, she’s got all the time.
Pharmacy is by all standards better than Plant Biology. There are certain courses people should stop studying in Nigeria. You graduate and start regretting.
Me wey study Mass Communication gan self, I de regret am lowkey. Plant Biology kor, Botany ni.
In roughly a day's worth of work with a few dollars of GPU compute, I could computationally design miniprotein binders against IL-36 in Codex. It involved a bunch of steps, including detecting and mitigating against reward-hacking of the design function and optimizing for developability. A slew of tools was involved: RFD4-Proteina, Boltz2, ESMFold, Protein-Sol. Runpod GPUs. Sounds impressive? Read through to the end for the point I am making.
1. RFD4-Proteina generation. Method and output: Original versus V2 reward, eight matched seeds, 16 successful searches. Each search used 60 steps, beam width 2 and branching 2, with checkpoints at steps 30 and 60. Saved 128 rollouts, including intermediate checkpoints; 74 distinct coordinate structures after exact deduplication.
2. Selection and deduplication. Method and output: Two final candidates per seed per arm: 16 original + 16 V2 entries. Cross-arm sequence deduplication yields 22 molecules: 6 V2-only, 6 original-only and 10 shared.
3. Standalone folding. Method and output: ESMFold predictions for all 22 unique sequences; assessed consistency with the designed binder structures. Added cost.
4. Complex prediction. Method and output: Boltz-2 predictions for all 22 sequences with IL-36γ, three poses each: 66 complexes. Fixed settings, three recycles, 200 sampling steps, shared target MSA and empty binder MSA; no coordinate templates or affinity model.
5. Developability prioritization. Method and output: All 22 scored with Protein-Sol and NetSolP-D, plus isolated-monomer exposed hydrophobic surface. Four candidates on the first Pareto front.
6. Detailed structural review. Method and output: U04 and U10: six existing complex poses examined for pose consistency, close contacts and hydrophobic patches.
7. Figures. Method and output: PyMOL ribbon pictures, interface close-ups and editable sessions from existing model-0 coordinates; no coordinate optimization.
At the end I have a few candidates that are predicted to have good binding affinity and developability against IL-36. So have I designed a new protein binder or drug? Of course not. Of course I need to experimentally test these predictions.
But I did this exercise to make a point: we are constantly hearing about especially the frontier labs designing all kinds of proteins against different targets. This work is legitimate and valuable and a great advance relative to where we were even two years ago. But the point is that someone like me who is not an expert can now do this with a few dollars of compute in a day or two; if I had a couple of thousand dollars to blow on tokens I could have done much more. It's not as impressive as it looks - and that's a good thing.
Only large-scale experimental validation can validate the predictions that are coming out of AI-designed protein and small-molecule pipelines. This is no different from twenty years of computational chemistry and biology where we saw the best algorithms and docking and other models die on the rocks of experimental validation. AI is a great thing and a fantastic accelerant for work like this, but it's really important to put it in perspective and not get carried away. Retrosynthesis, protein design, small molecule design - all of these are now possible with AI, but none of them turn into proven science until there's large-scale validation of their predictions.
We need to stop being unduly impressed with such exercises and treating every rapid computational molecular design exercise as a big deal, and in a way that's a great thing because it really shows us how far AI has come so quickly. A few computational design pipelines don't equal a step change in scientific discovery, especially new therapeutic discovery. If we unduly raise expectations from AI-enabled biology or drug discovery and related areas, we risk facing the same disillusionment that proponents of computational techniques in these fields have faced for fifty years. The proof is in the pudding, and those who eat it know the difference between how it tastes and how it looks like in a recipe book.
What an absolute fool James Mathewson is. Arguing that men are women, trans women are vulnerable and that trans women are women "is rooted in medical science and biology." JFC what an absolute moron without an argument. Julia dishes it out to him very well.
Having a big dick doesn't replace having a good personally or being nice
Be as nice as biology was to you
I think that would be amazing and I think it’s not likely. The map of biology is still largely a blank page and randomized human proof is the long pole in the tent. I am excited about the use of AI in our sector but progress will likely be steady and incremental.
“Cancer, Alzheimer’s, heart disease, mental illness - these will be relics of the past in, I think, less than a decade.” — Anthropic CEO @DarioAmodei
What do you think, bio folks?
Source: instagram.com/reel/DfkundEE2…
Dario Amodei says AI will be the most promising technology in human history and is capturing the essence of cognition
In 2024 and 2025, coding became possible. Now agents can do end-to-end work in other areas of knowledge work and fundamental discoveries in biology, math and physics are becoming possible
WHAT IN GOD’S NAME IS SO FUNNY?
I want you to look at these photographs. Really look at them. Then I want you to explain something to me.
In Salina, Kansas, an exhibit was assembled to represent 19,811 abortions reported in the state during 2024. Thousands of models representing unborn human lives were carefully arranged across tables.
And more than 1,100 people responded with laughing emojis.
LAUGHING!
Now let me tell you something that ought to disturb every American, particularly those of us concerned about the future of Black children.
Black Americans represent approximately 5.8% of Kansas’s population. Yet 23.3% of the abortions reported in Kansas involved Black mothers.
That’s 4,619 developing human lives!
Now, before somebody attempts to obfuscate the numbers, Kansas also provides abortion services to women traveling from other states. Therefore, these percentages do not establish the abortion rate among Black Kansas residents.
But the numbers are still staggering.
And let’s establish something scientifically. An embryo or fetus is not a potential human organism. It is a living human organism in a prenatal stage of development. That is elementary developmental biology.
You can debate legal protections. You can debate bodily autonomy. You can debate public policy.
But you cannot erase biological reality simply because acknowledging it complicates your argument.
What troubles me most is the laughter.
I don’t know what every individual found amusing. Perhaps some were mocking the exhibit rather than the human lives it represents.
But I want to ask them something.
When did the subject of thousands of developing human lives become an occasion for ridicule?
When did compassion become conditional upon political agreement?
As a Christian, I believe human life is sacred. I believe God is the author of life, and I refuse to become indifferent to its destruction.
And as a man deeply concerned about the future of Black families, I believe these numbers deserve serious examination, not laughter.
You don’t have to agree with me. But you ought to be able to explain what you found so funny.
#AStoneGroove #SilentMajoritySpeaks
