Our mission is to learn from evolution and redefine computing, using living neurons to make silicon-based AI models more stable, scalable and efficient.
San Francisco, California
Joined February 2026
- Tweets104
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- Followers3.7K
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More takes. Less waiting. More room for the idea you almost didn’t try.
mischief 1 is here. Go make something.
today, we introduce a little mischief to the world.
for four years, we’ve been brewing real brain cells on electrodes to understand how they compute. now, we’ve turned those discoveries into a video model anyone can use.
from 0.5¢ a second, mischief 1 is at least 5x faster than its base and the cheapest image-to-video model on @fal and @OpenRouter. soon to be on @awscloud marketplace.
it’s not a delusion anymore. biocompute is real, commercial and this is just the beginning.
happy halloween.
A little imagination and a whole lot of mischief at @TechCrunch Founder Summit.
Watching people bring their ideas to life in the palms of their hands. 5-second videos generated in just 5.8 seconds on average.
The reaction? “Wait, how are you doing this?”
Wait, what?
We grow living neurons on electrode arrays, encode information with patterned electrical stimulation and record how the network processes it over time. We study things like recurrent dynamics and how activity settles into stable patterns. We then translate those observations into algorithms that make AI more efficient and runs on GPUs.
What happens when you take the cost and time constraints out of creativity? @JustinHackney33 gives us a glimpse of what's possible.
2,511 clips. five seconds each. 720 p.
$125.55 total.
that’s what @JustinHackney33 of @WonderStudiosX, who made our launch film, generated with mischief 1. generating that much video with wan 2.2 would cost about $1,017.
the point isn’t just cheaper video. it’s the freedom to follow an idea without rationing every take.
@JustinHackney33 came to our lab to see where it starts.
The Biological Computing Co. (TBC) retweeted
A little mischief for Halloween 🎃
mischief 1 from The Biological Computing Co. turns an image into video, using four years of research on real brain cells grown on electrodes.
From $0.005 a second, live now on OpenRouter.
openrouter.ai/tbc/mischief-1
TBC mischief 1 is now live on OpenRouter 🧠🎬
Image-to-video from The Biological Computing Company: give it a starting image and a prompt, get back a 3s or 5s clip at 480p or 720p.
From $0.005 per second of video.
openrouter.ai/tbc/mischief-1
today, we introduce a little mischief to the world.
for four years, we’ve been brewing real brain cells on electrodes to understand how they compute. now, we’ve turned those discoveries into a video model anyone can use.
from 0.5¢ a second, mischief 1 is at least 5x faster than its base and the cheapest image-to-video model on @fal and @OpenRouter. soon to be on @awscloud marketplace.
it’s not a delusion anymore. biocompute is real, commercial and this is just the beginning.
happy halloween.
Such an important alternative for the whole technology
today, we introduce a little mischief to the world.
for four years, we’ve been brewing real brain cells on electrodes to understand how they compute. now, we’ve turned those discoveries into a video model anyone can use.
from 0.5¢ a second, mischief 1 is at least 5x faster than its base and the cheapest image-to-video model on @fal and @OpenRouter. soon to be on @awscloud marketplace.
it’s not a delusion anymore. biocompute is real, commercial and this is just the beginning.
happy halloween.
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i really would like to use this as the base of my next short film . here is my latest work xitter.twitterapi.xyz/LinAiDreams/status/210…
THE BEACON OF NUJOOM | منارة النجوم Some lights guide us home. Others must never go out. On a remote Mediterranean coast, Leila returns to the watchtower her late father once tended. She intends to finish her work and leave by sunrise. But as night settles over the sea, an unexpected visitor arrives with an intimate knowledge of her father and an offer that touches her deepest longing. Surrounded by the machinery he maintained and the small traces of life he cherished, Leila must confront what it means to keep his memory alive, and how far she might go to escape the pain of losing him. An atmospheric supernatural short film about grief, faith, and the fragile boundary between comfort and deception, The Beacon of Nujoom follows one woman through a night when a solitary duty becomes profoundly personal. How do you let go of someone you would give anything to see again? made with
@runwayml
agent , seedance 2.5 , claude opus 5.5 and a human soul touch.
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The Biological Computing Co. (TBC) retweeted
This is honestly one of the most fascinating developments in AI I've seen in a while.
A startup called The Biological Computing Co. just launched Mischief 1, an AI video generation model developed using research from actual living human brain cells. The company says its technology makes video generation 5 times faster while reducing costs by roughly 80%. For the past four years, they've been growing living neurons in laboratories and connecting them to thousands of electrodes to study how the human brain processes information. Think about it because our brains can process enormous amounts of information while consuming relatively little energy, whereas AI models require massive amounts of computing power and electricity.
What makes this interesting is that they're taking what they learn from these living neurons and translating those discoveries into software that makes existing AI models significantly more efficient. The brain cells aren't directly generating the videos but rather helping researchers discover entirely new ways to optimize AI. And the economics are incredible. Mischief 1 starts at just half a cent per second of generated video. It's already being made commercially available through fal and OpenRouter, with plans to expand onto AWS Marketplace.
But I think the opportunity here goes WAY beyond video generation. Imagine applying this technology to large language models, robotics, autonomous vehicles, and other AI applications. If companies can get significantly more performance from the same computing infrastructure, it could completely change the economics of artificial intelligence. Think about how much Microsoft, Google, Meta, and Amazon are spending on AI infrastructure. Even modest improvements in computational efficiency could translate into billions of dollars in savings at their scale, while allowing them to build even more powerful AI systems. And this could be just as exciting for companies like NVIDIA and AMD. As AI becomes cheaper and more efficient to run, it becomes practical to deploy in more products, industries, and applications, potentially driving even greater demand for computing power.
I think the biggest takeaway is that the next major breakthrough in AI might not come from building bigger models or adding more GPUs but rather from understanding how the human brain computes and applying those discoveries to artificial intelligence. We're literally using living brain cells to help make AI better, and this could be just the beginning of an entirely new approach to computing.
🤝 Paid partnership
today, we introduce a little mischief to the world.
for four years, we’ve been brewing real brain cells on electrodes to understand how they compute. now, we’ve turned those discoveries into a video model anyone can use.
from 0.5¢ a second, mischief 1 is at least 5x faster than its base and the cheapest image-to-video model on @fal and @OpenRouter. soon to be on @awscloud marketplace.
it’s not a delusion anymore. biocompute is real, commercial and this is just the beginning.
happy halloween.
it's pretty wild. we study how living neurons compute and turn those discoveries into faster, more efficient AI on today's hardware. step into our lab and come visit us in person: youtube.com/watch?v=R4eKRihw…
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I got the chance to work on the landing page for a new video model from a lab that grows real brain cells.
insanely cheap at half a cent a second.
had a lot of fun creating three.js concepts with opus 5.5. here's my workflow.
check out mischief-1: app.tbc.co
today, we introduce a little mischief to the world.
for four years, we’ve been brewing real brain cells on electrodes to understand how they compute. now, we’ve turned those discoveries into a video model anyone can use.
from 0.5¢ a second, mischief 1 is at least 5x faster than its base and the cheapest image-to-video model on @fal and @OpenRouter. soon to be on @awscloud marketplace.
it’s not a delusion anymore. biocompute is real, commercial and this is just the beginning.
happy halloween.
Incredible work @MengTo. This is a video worth watching.
I got the chance to work on the landing page for a new video model from a lab that grows real brain cells.
insanely cheap at half a cent a second.
had a lot of fun creating three.js concepts with opus 5.5. here's my workflow.
check out mischief-1: app.tbc.co
This is a great model for exploring ideas quickly and cheaply.
It's an image-to-video generation model. 5x faster and 80% lower inference cost than its base open-weight model.
• Input: a starting image and a prompt describing what you want
• Output: a 720p video
• Advantages: Fast generation, low cost. Easy to iterate.
• Disadvantages: Output doesn't have production quality.
today, we introduce a little mischief to the world.
for four years, we’ve been brewing real brain cells on electrodes to understand how they compute. now, we’ve turned those discoveries into a video model anyone can use.
from 0.5¢ a second, mischief 1 is at least 5x faster than its base and the cheapest image-to-video model on @fal and @OpenRouter. soon to be on @awscloud marketplace.
it’s not a delusion anymore. biocompute is real, commercial and this is just the beginning.
happy halloween.
At Wonder, we're lucky to be working with some of the most frontier companies in the world, pushing boundaries of what's possible
TBC's model, Mischief, uses real lab-grown neurons to make video generation faster and cheaper
A pleasure to work with the team to bring this vision to life @AlexKsendzovsky @BioComputingCo
today, we introduce a little mischief to the world.
for four years, we’ve been brewing real brain cells on electrodes to understand how they compute. now, we’ve turned those discoveries into a video model anyone can use.
from 0.5¢ a second, mischief 1 is at least 5x faster than its base and the cheapest image-to-video model on @fal and @OpenRouter. soon to be on @awscloud marketplace.
it’s not a delusion anymore. biocompute is real, commercial and this is just the beginning.
happy halloween.
Our big bet: the next great compute multiplier will come from biology.
Instead of just adding more chips and power, we study how living neurons compute and turn those discoveries into faster, more efficient AI on today's hardware.
More from the compute we already have.
@BioComputingCo Let's try this:
A tiny ghost rings a doorbell. A terrifying demon opens the door, sees the ghost, screams in fear, and slams the door shut. The confused ghost shrugs and floats away. Cinematic, photorealistic, hilarious timing.
Can you generate a video for me?
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