Konrad kording, @Penn Prof, deep learning, brains, #causality, rigor, https://xitter.twitterapi.xyz/t.co/tTJW05RRfa, https://xitter.twitterapi.xyz/t.co/qf7ZHxjaK1, Transdisciplinary optimist, Dad, Loves outdoors, 🦖
Philadelphia, PA
Joined November 2012
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Kording Lab 🦖 retweeted
Brute force computation is not enough for intelligence. Clever new methods are needed. The science of AI is far from finished. IMHO
Kording Lab 🦖 retweeted
I'm not gonna share something I merely vibe-coded. If it's going in front of human beings, it's gotta have human effort put into it.
Kording Lab 🦖 retweeted
How do we understand neural nets with so many interacting params that we can’t describe what they do in words?
Our take: objective functions and regularizers offer a concise description of "what models learn"
Can we *empirically* study implicit regularization in DL?🧵
Everyone in AI should hold put options for AI. I sure do. AI to the moon? You gain because your future incomes are a bet on AI. AI loses? Your portfolio gains.
In canada the applicants to grants are allowed to use AI and the reviewers are not. That seems wrong. (chatgpt, which prompt did this author use? :) ) science.gc.ca/site/science/e…
I have a new talk explaining how modern AI works for a curious lay audience. Never given it. What would be the ideal venue for such a talk?
Computer vision and connectomics jobs at mindspan just dropped. mindspan.org/jobs Build deep learning models for the one of the world's largest segmentation jobs. Build great and robust pipelines. Annotate or proofread. Mindspan is hiring.
Kording Lab 🦖 retweeted
How many times have you seen a mouse study claiming that a therapeutic works, and the survival curve looks like this? Broken axis, 6% difference in survival time, but the P value is < 0.05 and it's claimed as a positive result. It's not. In my 15 years of prion science, I have learned to look past such claims almost instantly. Yet sometimes these claims still lead to high-profile publications, millions of dollars in funding, and even to therapies being tested clinically. In this new blog post I release data on 301 untreated control animals from our last 9 years of in vivo studies, model out the various ways that P values can appear significant even when the result is null, and put into words the intuition I've built up as to which claims are believable and which are not.
cureffi.org/2026/11/03/how-t…
Kording Lab 🦖 retweeted
@AllenInstitute OpenScope is undergoing a big transformation to become the Global Brain Observatory.
Brain-wide recordings shared with the entire world. Large, public experimental projects for the big neuroscience questions of our time. We are hiring.
Kording Lab 🦖 retweeted
Neurotech is Humanity’s Next Frontier!
I’ve been investing in neurotech since 2021 and working with teams building BCIs, NeuroAI, and connectomics. It now feels like AI did in ~2019.
We are entering an extraordinary era: neurotech already restores functions, it can enhance our capabilities, and will evolve what it means to be human.
PLC Neurotech is the fund backing the extraordinary founders and defining companies of this booming industry.
Kording Lab 🦖 retweeted
We're looking for nominations for a speaker series hosted by the Kording lab @ Penn in Spring 2027!
The goal is to invite (mostly early-career) researchers in computational neuroscience, machine learning, AI, and other related fields for a small-group in-depth discussion of their work
Nominations (including self-nominations) can be made through the attached form.
forms.gle/8R3moDRwVvTu74fE8
Kording Lab 🦖 retweeted
This is going to really help in all those search and rescue operations that fail because the lost person ran terrified into the forest to get away from their rescuers
Purdue University's IDEAS Lab built an autonomous drone that tracks runners through dense forests completely without GPS or cloud networks.
By running 3D LiDAR mapping and obstacle-avoidance AI entirely on-chip, it can weave under tree canopies and predict target movement through blind spots in real time.
Massive implications for next-gen search & rescue and edge AI.
Kording Lab 🦖 retweeted
An unanticipated pleasure of publishing a book has been the excuse to interact with friends & colleagues in some of my favorite places (like bookstores!). Yesterday I finished the 7th of 7 book events in October, starting and ending in California. Here are some quick highlights!
Kording Lab 🦖 retweeted
One gram! One-photon (not two-photon) mesoscope.
Cool work.
Our recent work presents a 1-gram wireless mesoscope for cortex-wide imaging at single cell resolution in naturally behaving mice, published in @Nature . It's interesting to see large-scale neural activities in multiple mice within a very natural habitat. rdcu.be/iGFq4KbdWuza
A lot of people believe that interacting with ai makes their ai better (“they train it”). I have have seen pretty little of that provided one is a little bit mindful about context. I have not seen convincing publicstions. Am i missing something? I mean sure there is some academic work (eg LaMP, LongMemEval, Memora …) but nothing seems to really matter.
Kording Lab 🦖 retweeted
If governments tax AI to limit mass unemployment: tax data centers, not tokens.
Taxing AI investment (data centers) can lower peak unemployment. Taxing AI deployment (tokens) mostly delays it.
Either way, a second-best, temporary tool.
From my @IMFNews panel 🧵
Intelligence saturation. Everyone called us crazy ;)
OpenAI, Anthropic and other leading AI labs face a growing challenge: Better models aren't necessarily attracting more usage. A 10-point intelligence advantage now earns just 20% more developer traffic, down from nearly 69% in late 2025.
Full story: thein.fo/4hGJ9jY
Why We Systems Neuroscientists Should (Usually) Be Quietists: The Philosophical Logic of NeuroAI -- response to David Barack kording.substack.com/p/why-w…
