Nature Reviews Cancer

🍂 Our November issue is now live!🍂 It features #Reviews on: - Brain barriers in glioma - Neutrophils in cancer - 3D chromatin remodeling - Single cell sequencing for genotype-phenotype mapping Check it out 👇 dlvr.​it/TW672j

NEW content online! 3D models to capture and perturb tumour heterogeneity in vitro dlvr.​it/TWH3T1

NEW content online! Origins and heterogeneity of colorectal cancer dlvr.​it/TWDPXT

NEW content online! Astrocytes drive stroke-induced glioma progression dlvr.​it/TWBcrh

#ResearchHighlight García-Gómez et al. identify an adaptive proliferative pause program that supports the survival of micrometastatic cells during early brain colonization and uncover therapeutic opportunities to target this state. 📖 👇 dlvr.​it/TW8sRY

🚨 #REVIEW 🚨 Sofias et al. discuss recent advances in radiotheranostic strategies, advances in nanotheranostic and microtheranostic platforms, and image-guided therapeutic and surgical interventions in oncology. 📖 👇 dlvr.​it/TW72Ll

#ResearchHighlight Obesity is a modifiable risk factor associated with increased tumour incidence and aggressiveness. Curtin et al. identify an oxylipin secreted by lean adipocytes that suppresses breast cancer progression. 👇 dlvr.​it/TW6Hyn

NEW content online! Single-cell tumour phylogenetics dlvr.​it/TW492K

NEW content online! Cancer theranostics dlvr.​it/TW1g0B

NEW content online! Hit the pause button dlvr.​it/TW1R8n

NEW content online! Lean, mean, breast cancer-fighting machine dlvr.​it/TVxYXj

🚨 #PERSPECTIVE 🚨 The dark proteome comprises previously undiscovered proteins arising from alternative genomic loci or altered translation. Presner et al. review what we know, and what's needed to unlock its clinical potential. dlvr.​it/TVwnqt

Gastric and oesophageal cancers caused more than 1 million deaths worldwide in 2024. In this Comment, Cancer Grand Challenges explain how they have launched two targeted challenges to address this unmet need. #COMMENT dlvr.​it/TVw10d

🚨 #REVIEW 🚨 Morgan, MacPherson & Lum examine how metabolism integrates with CAR T cell design, outline metabolic engineering solutions & highlight opportunities to leverage diet to improve CAR T cell efficacy. dlvr.​it/TVvDp9

Some health systems struggle to provide follow-up care for the growing number of cancer survivors. In this #Comment, Ganz explores how survivorship can better address the long-term psychosocial needs of cancer survivors. dlvr.​it/TVtTKX

NEW content online! The urgent challenge of gastroesophageal cancer dlvr.​it/TVrY16

NEW content online! Mapping the functional dark proteome in cancer dlvr.​it/TVqzSx

NEW content online! Boosting CAR T cell efficacy in cancer with metabolic insights from design to diet dlvr.​it/TVq9v5

NEW content online! Supercentenarians’ superpower to suppress cancer dlvr.​it/TVlFG5

NEW content online! Engineered models of metastasis dlvr.​it/TVlF6k