Pathology and Laboratory Medicine @Penn: AP, CP, Research, Transfusion Medicine & Therapeutic Pathology, and Precision Dx
Philadelphia, PA
Joined February 2014
- Tweets5.4K
- Following927
- Followers3.4K
- Likes1.1K
We are looking forward to next Monday's Grand Rounds with Dr. Daniel Brat, MD, PhD! Should be an engaging session on how molecular discoveries continue to reshape the classification, diagnosis, and management of these tumors.
How has molecular pathology changed the way we view diffuse gliomas?
I'm delighted to welcome Dr. Daniel Brat, MD, PhD, Chair of Pathology at Northwestern University Feinberg School of Medicine, as an upcoming speaker in our Department of Pathology & Laboratory Medicine Grand Rounds series at Penn.
Dr. Brat will present "A Contemporary Molecular View of Diffuse Gliomas," highlighting how molecular discoveries continue to reshape the classification, diagnosis, and management of these tumors.
We look forward to an engaging discussion with one of the field's leading experts.
@DanielJBrat
@NorthwesternU
@Sciencedirect
#ScienceDirect
@TheUSCAP
@ESP_Pathology
@AACR
@IARCWHO
@PennPathLabMed
2
98
Thank you to Daniel Ackerman, PhD, for his engaging Grand Rounds yesterday on the "Prevalence and Breakpoint Heterogeneity of PSIP1::TBL1X Fusions in Pancreatic Neuroendocrine Tumors". Always great to learn from our amazing colleagues in other areas of @PennMedicine!
1
133
🎉 Congratulations Jonni Moore, PhD, on receiving the Thomas Jefferson University (@JeffersonUniv) College of Life Sciences 2026 Distinguished Alumni Award! We could not think of a more deserving recipient and are so fortunate to have you on our team!
157
A great recent publication by @carina_dehner in @ModernPathology investigated a series of nine morphologically classic DNSMs and performed molecular testing & demonstrates the first recurrent molecular alteration identified in this tumor type.
🔬: modernpathology.org/article/…
🎉 Congratulations to Dr. Raj Singh, @mydermpath, on recently being named a member of @pathologistmag's Power List Hall of Fame for pathologists and scientists whose impact on the field will last beyond their lifetimes!
🔬: thepathologist.com/power-lis…
There is a new 🎙️ Precision Pathology Podcast out! In this episode hear our chair @DrNetto in conversation with Dr. Yuri Tolkach as they discusses his team's study analyzing 2,791 whole-slide images using an open-source AI model.
🔬: podcasts.apple.com/us/podcas…
New Precision Pathology Podcast Episode!
Can computational single-cell profiling of routine H&E slides reveal prognostic clues in lung adenocarcinoma?
In this episode of Precision Pathology, Dr. Yuri Tolkach discusses his team's study analyzing 2,791 whole-slide images using an open-source AI model. The research identified lymphocyte-rich tumor environments as favorable prognostic markers, while granulocyte-rich stromal patterns were associated with poorer outcomes.
The study also demonstrates how spatial immune-tumor interactions can provide powerful prognostic information, highlighting the potential of computational pathology to enhance risk stratification using standard pathology slides.
Read manuscript here: doi.org/10.1016/j.prpath.202…
Listen to the full episode: clientfiles.doctorpodcasting…
Also available on Apple Podcasts, Spotify, YouTube, RadioMD, and other major podcast platforms.
@y_tolkach
@ChemUniCologne
@Sciencedirect
#ScienceDirect
@TheUSCAP
@ESP_Pathology
@AACR
@IARCWHO
@PennPathLabMed
#PrecisionPathology
#LungAdenocarcinoma
#ComputationalPathology
#DigitalPathology
#TumorMicroenvironment
#AI
#WSI
#NSCLC
#cellularneighberhoods
Penn Path & Lab Medicine retweeted
Congratulations to Robert Vonderheide (@PennCancer) & Andrew Rech (@PennPathLabMed) on being named the @AACR Scientific Achievement Honoree & Early Career Investigator Honoree, respectively! tinyurl.com/zxemwrvm
🎉 Congratulations to Don Siegel, MD, PhD, on receiving the Emily Cooley Award & Memorial Lectureship at the recent AABB Annual Meeting! Members of the Penn PLM team past and present joined him to celebrate & Vijay Bhoj, MD, PhD, presented the award.
🔬: aabb.org/membership/get-invo…
7
402
Penn Path & Lab Medicine retweeted
ft. Ryohei Watanabe, Benjamin Creekmore, Nabil Darwich, @neuro_smith, Hong Xu, @AngelinaB829, Sacha Salphati, Lakshmi Changolkar, Kevt'her Hoxha, Bin Zhang, Caroline O'Rourke, Virginia Lee, @TNRLab (@PennPathLabMed), @GMBurslem & @yiweichang (@BB_UPenn) nature.com/articles/s41594-0…
A @NatMetabolism paper by Daniel Powell, PhD & Roddy O'Connor, PhD provides a clue to why T-cell-based immunotherapies don’t work very well against ovarian cancers, showing the impact of the ovarian cancer tumor environment & suggesting a new strategy.
🔬: nature.com/articles/s42255-0…
121
An insightful plenary session with Rajendra Singh MD, Professor of Pathology at the University of Pennsylvania, explored how artificial intelligence is transforming everyday pathology workflows.
#PathVisions26
2
198
Wonderful to have Dr. Annette Kim (back) on campus today to give an engaging Grand Rounds talk! It was a packed house and our team greatly appreciated her thoughtful take on addressing the gaps in precision medicine.
Penn Path & Lab Medicine retweeted
Congratulations to @joeyzacks (@PennPathLabMed), recipient of the Michael S. Brown New Investigator Research Award! Learn more about Dr. Zackular & his work here➡️tinyurl.com/282uu2ju #PSOMAOE @CHOP_Research
Excited to see our faculty member Don Siegel, MD, PhD's upcoming talk at the @ASCP_Chicago 2026 Annual Meeting highlighted by @pathologistmag! Be sure to check it out if you are attending in November.
🔬: thepathologist.com/issues/20…
146
Penn Path & Lab Medicine retweeted
So proud of our @PennPathLabMed trainees working on this project @ktmontone @DrNetto @IACytology @DiagnosticCyto @CancerCytopath @EfcsYoung
karger.com/acy/article/doi/1…
🎉Congrats to Joseph Zackular, PhD and Mingyao Li, PhD on receiving a 2026 Penn Medicine Award of Excellence! Dr. Zackular received the Michael S. Brown New Investigator Research Award & Dr. Li the Michael P. Nusbaum Graduate Student Mentoring Award.
🔬: med.upenn.edu/evpdeancommuni…
Exciting things are happening with #Pathology and #AI! To learn more about how our faculty member, @ZhiHuangPhD, is training AI models to "think" like humans, check out this article in @LiveScience
🔬: livescience.com/health/cance…
Wondering what is next in CAR T-cell therapy research? Check out this interview article with @carlhjune in @AACR.
🔬: aacr.org/blog/2026/08/25/dri…
1
121
🎉 Congratulations to Dr. John Lambris, @LambrisJD, on receiving the impressive 2026 Biochemical Analytics Award from the German Society for Clinical Chemistry and Laboratory Medicine (DGKL) for his groundbreaking research on the human immune system!!
🔬: medlabportal.com/medlabaward…
Great to see Penn PLM Faculty, @carlhjune featured in this @USATODAY piece on ambitious research projects. “To have a big impact you need to go for the three-pointers,” says June.
🔬: usatoday.com/story/news/2026…
1
170