Professor & Dattels Family Chair at The Jackson Laboratory @jacksonlab studying hematopoietic stem cell biology, aging & cancer. 🇨🇦🇺🇸 Tweets are my own.
Bar Harbor, Maine
Joined November 2015
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Thrilled to share that our Stem Cells & Developmental Biology program at JAX is officially launched. 40 PIs. 60+ trainees. >$160M in active NIH funding. Fundamental discovery and translational platforms — in the same world.
🔬 go.jax.org/stem-cell-researc…
#JAXresearch #JAXstemcellsdev
Congratulations Xiaodi! Transgene characterization is fundamentally important to better understand and maintain our key mouse resources!
For years, lab lore was that the workhorse Scl-CreERT transgenic driver is integrated on mouse chr4, thanks to yeoman’s work tracking genetic crosses by @sanchezvelamd. In 2024, we decided to find its exact locus of integration by inspection of aligned Illumina short-read WGS. /1
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Returning home from the Karolinska StratRegen retreat as a keynote speaker. I heard inspiring science spanning bioengineering, aging, stem cell & organoid models, immunology, regeneration, & more. Fantastic to catch up with my postdoc labmate Sidinh Luc after nearly 10 years!
Can we interrupt the inflammatory signals driving clonal hematopoiesis? Our new study, led by @jaynathemistry, identifies neutrophil-derived S100A8/A9 as a potential therapeutic target to limit DNMT3A-mutant stem cell expansion. @Haematologica
doi.org/10.3324/haematol.202…
It’s been a big few weeks for Stem Cells & Developmental Biology at The Jackson Laboratory! A thread🧵 #JAXresearch #JAXstemcellsdev jax.org/research-and-faculty…
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🔬 Nearly 450 experts gathered at The Rockefeller University for the first joint JAX-NYSCF Conference, marking 20 years since the discovery of iPSCs and 20 years of the NYSCF Conference. Thank you to all who joined and to our sponsors.
jax.org/news-and-insights/20…
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Peter @vangalenlab and I are very appreciative and grateful for the support of the Waxman Institute @WaxmanCancer to pursue our exciting collaborative studies!
#BloodCancerAwarenessMonth #JAXresearch #JAXstemcellsdev
We're proud to fund @TrowbridgeLab & @vangalenlab as they investigate how age-related inflammation may fuel blood cancers—and uncover potential paths to prevention. This is why connecting aging biology & cancer research matters! with @TheMarkFdn #BloodCancerAwarenessMonth
Very grateful for the support of @TheMarkFdn to pursue our biggest and boldest ideas!!
#BloodCancerAwarenessMonth #JAXresearch #JAXstemcellsdev
This #BloodCancerAwarenessMonth, we’re spotlighting 2023 Emerging Leader Award winner Jennifer Trowbridge (@TrowbridgeLab) of @JacksonLab. She’s looking for answers to a big question: why aging blood cells develop into cancer in some individuals but not others.
The Jackson Laboratory is a wonderful, collaborative place to pursue basic & translational science. On the faculty job market? I strongly encourage you to consider joining us in Bar Harbor, Maine!
Apply: go.jax.org/276n55
#JAXresearch #JAXstemcellsdev
More on our Stem Cells & Developmental Biology program below. Questions welcome!
jax.org/research-and-faculty…
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Bittersweet to say goodbye to our lab manager @griffin_nye after 5 years. He's kept the lab running & brought endless enthusiasm along the way. So grateful for all he's given. I'll miss him, but I'm excited to see him follow his dream of becoming a teacher! 🩷
I had the privilege and joy of returning yesterday to the @DanaFarber and @BostonChildrens where I did my postdoctoral training, this time as an invited speaker. Grateful to Zuzana Tothova for hosting me! It was a full circle moment and can't wait for the next time 😁
Thank you to The Waxman Institute @WaxmanCancer for supporting our research!!
We are thrilled to be supporting such amazing researchers, including @TrowbridgeLab and @RossLevineLab. Check out all our funded research teams here: waxmaninstitute.org/our-rese…
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We are grateful for support from The Mark Foundation for Cancer Research @TheMarkFdn!! Particularly for high-risk, high-reward endeavors that are challenging to fund through conventional mechanisms.
New in @Nature: Insights on pre-malignant clones from ELA and Aging & Cancer grantee @TrowbridgeLab, Momentum Fellow Inés Fernández Maestre, and Scientific Advisory Committee chair @RossLevineLab! nature.com/articles/s41556-0…
With mixed emotions, we said farewell to our summer student Eva Rios. She was a JOY to have in the lab - thoughtful, engaged, creative, a dot-connector and with a great sense of humor and desire to learn and be challenged 🤩 #SSP26 #JAXGenomicEducation #JAXstemcellsdev
New work from our lab out today in @NatureCellBio led by @jaynathemistry!!
nature.com/articles/s41556-0…
🧵 on how clonal hematopoiesis turns the bone marrow niche into an accomplice:
A huge congratulations to the newest graduate of the Trowbridge lab, Dr. Shawn David!! Shawn did a fantastic job defending his thesis today. So proud! 🎉 👏 🎊 #JAXGenomicEducation #UMaineGSBSE #JAXresearch #JAXstemcellsdev
📢 BIG NEWS in ISEH's journal Experimental Hematology!!! 2 new article types specifically designed for research often difficult to publish: validated protocols, null results, phenotyping & high-value datasets. Plus fast-track review + a $650 incentive!
🔗 iseh.org/Publications/ExpHem…
📢 Experimental Hematology, the official journal of ISEH, has launched new article types and author incentives! View the latest updates and submit your next manuscript: iseh.org/Publications/ExpHem…
An awesome new mentoring opportunity for trainees offered by @ISEHSociety! Congrats to @AlbaRMeira and other advocates for envisioning and launching this program!!!
The @ISEHSociety Inaugural Mentoring Program is open for applications! This is one of the programs that I wished existed when I was transitioning to my next academic position. If you are a PhD student or postdoc thinking about your next career step, apply now! Deadline July 31st.
#ISSCR2026 is a wrap - so what's next? 🔬
The JAX-NYSCF Conference
Sept 23–24 | The Rockefeller University, NYC
Fabulous program and registration is open! See you there!!
conference.nyscf.org/
#JAXresearch #JAXstemcellsdev
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It's the final day of #ISSCR2026! Today Justin McDonough from JAX receives the 2026 ISSCR Public Service Award as part of Stem Cell COREdinates and CorEUstem. 🏆
79 institutions. Shared standards. Global access. The infrastructure that enables discoveries. 👇
Day 3 of #ISSCR2026 🔬 JAX stem cells & development colleagues present new translational work on diabetes and vision loss! 👇 Final day tomorrow, and something special for JAX. Stay tuned. 🏆
#JAXresearch #JAXstemcellsdev
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