Zero Prime VC (@ZeroPrimeVC) header
Zero Prime VC (@ZeroPrimeVC) profile picture

Early stage fund supporting deeply technical founders launching enterprise AI, data infrastructure & devtools startups.

SF
Joined June 2023
Photo by Zero Prime VC (@ZeroPrimeVC)Photo by Zero Prime VC (@ZeroPrimeVC)
We’ve cut the cost of an agent conversation 75% this year, even as the agent got far more powerful, with more context and more background curation. Our CTO Caitlin Colgrove on how we did it, and why we optimize for intelligence per dollar, not tokens.
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Vulnerability disclosures doubled this year, and most of the AI in the “Black October” story worked for defenders: AI tools found the most serious bug on the list before it was widely exploited, and of the 28 incidents in the viral list, nine had a documented AI connection, with none traced to AI-written attacks. The real damage came from long-lived credentials stored in shared places. Railway, Zeabur, TiDB Cloud, and LiteLLM all came down to one key sitting in one place with access to many systems. We went through all 28 incidents against primary sources. Here’s what actually happened, and what to patch this week. readyset.io/blog/black-octob…
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Today we’re announcing our $100M raise, led by @peakxvpartners and @137ventures, with @AvraCap, @a16z, @sequoia, @Redpoint, @ZeroPrimeVC, and @AmplifyPartners all joining the round. And that’s not all: we’re also launching Hex 4.0, a new foundation built for agents. Everything is code, so agents can work with your data and people can verify every number. This round lets us keep building on that foundation without slowing down growth or hiring. More on Hex 4.0 later today. We’re deeply grateful to the 2,500+ teams building on Hex. There’s still so much to build, and it’s never been a better time to work with data. Hear more from our CEO, @barrald → lnkd.in/e7A2UNPe
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Zero Prime VC retweeted
Time well spent at @raiseconference last week. On Thursday I presented @ZeroPrimeVC to a room of 100 GPs & 300+ LPs. I shared the story of how Zero Prime got started + our unique approach to investing in AI software infra. I like to say we’ve hosted “baby Databricks” and “baby Snowflake” at early @AICouncilConf events. Year after year, I watched the engineers in our community go off and start companies, and Zero Prime grew out of wanting to back them. 5 of the 6 companies on this slide have founders who’ve been on our stage. @bernhardsson gave a talk at our NYC meetup in 2013, when he was still at Spotify. @williamfalcon spoke at DataEngConf in 2017 as CTO of a student-loan startup. @tejasmanohar and @barrald sat down with me on my podcast in 2021, and @alexmashrabov joined us this year. Huge thanks to the RAISE team for inviting me to tell that story a stage, and thank you @deniseyezi for this capture!
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Muse Spark Open, a coding-optimized open weight model from @Meta, is now available on Modal. Muse Spark Open is the most capable US open weight model to date and is trained specifically for agentic coding and long-horizon tasks; it supports native multimodal understanding and supports a 1M token context window.
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Zero Prime VC retweeted
Modal, CuspAI, LanceDB and 5 other Zero Prime portcos are hiring for technical roles across AI/infra right now. Here are the freshest, all posted in the last 3 weeks: @modal | cloud infra for AI ➔ Analytics Engineer (NYC / Stockholm / SF) jobs.ashbyhq.com/modal/a518f… ➔ Member of Technical Staff, Storage (Stockholm) jobs.ashbyhq.com/modal/34858… ➔ Member of Technical Staff, SDK (Stockholm) jobs.ashbyhq.com/modal/a65df… ➔ Member of Technical Staff, Inference Runtime (SF) jobs.ashbyhq.com/modal/6195f… @cusp_ai | AI-powered materials discovery ➔ Research Engineer, Materials Foundation Models (Cambridge UK / Amsterdam / London / Berlin) jobs.ashbyhq.com/cuspai/db0d… @hexanalytics | the analytics platform for humans and agents ➔ AI Engineer Intern (SF) jobs.ashbyhq.com/hex/f2562cd… ➔ Engineering Director, AI Engineering (SF / NYC) jobs.ashbyhq.com/hex/1377177… @lancedb | multimodal lakehouse for AI ➔ Documentation Engineer (US / Canada) jobs.ashbyhq.com/lancedb/ec9… ➔ Senior System Test Engineer (US / Canada) jobs.ashbyhq.com/lancedb/0ec… @LightningAI | full-stack AI infrastructure platform ➔ Senior Infrastructure Operations Engineer, EMEA (London) job-boards.greenhouse.io/lig… @runware | unified AI inference API ➔ Creative Engineer / AI Creative Technologist (UK / Spain / France) apply.workable.com/j/CE2C2FF… ➔ Senior / Lead Cooling Systems Design Engineer (Bucharest) apply.workable.com/j/FF7C5B8… @Freshpaint_app | healthcare marketing performance & compliance platform ➔ Enterprise Implementation Engineer (US, remote) jobs.ashbyhq.com/freshpaint/… @higgsfield | AI-native creative suite ➔ Data Scientist, Antifraud (Kazakhstan) jobs.ashbyhq.com/higgsfielda… ➔ Data Analyst, Antifraud (Kazakhstan) jobs.ashbyhq.com/higgsfielda… We're hiring too, for @ZeroPrimeVC and @AICouncilConf (SF, in person): ➔ Growth Marketer zeroprime.notion.site/Growth… ➔ Chief of Staff zeroprime.notion.site/Chief-…
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Zero Prime VC retweeted
Next Wednesday morning @TheoryVC & @ZeroPrimeVC are taking over one of SF's best-kept matcha secrets in SoMa as part of SF @Techweek_. Drop by anytime between 8am and noon, get caffeinated with us, and meet other founders and builders across AI and software. We'd love to see you. RSVP Required: partiful.com/e/D8y8XoMl52Wgw…
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I’m hiring a Chief of Staff to help build the next chapter of @AICouncilConf & @ZeroPrimeVC. Most of your time will go toward running and growing AI Council. You’ll also work closely with me across both orgs to get important work done. This is for an unusually capable generalist. The scope is intentionally broad and expected to grow. The right person will earn ownership quickly and can develop toward broader operating leadership over time. Full time, in person in San Francisco (office near Jackson Square). Base salary of $150,000–$180,000, based on experience. Role and application details: zeroprime.notion.site/Chief-… If someone comes to mind, send this their way.
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Zero Prime VC retweeted
Build your own harness. This is a seriously good paper from NVIDIA on self-improving agent harnesses. The paper is called SoL-Pi, out of NVIDIA, NTU and MIT. Every coding agent runs inside a harness. That's the layer that reads files, runs commands, manages memory and talks to the model. Humans tune it by hand, reading long execution logs and turning what they notice into code changes. They handed the job to an AI instead. A research AI watched a coding agent work, proposed changes to the harness, tested them, and kept only what saved tokens without hurting results. It ran about 150 research directions across roughly 500 environments, more than 3,000 runs and over 60,000 agent-environment interactions. Four fixes survived. 1. The agent edits a file and runs the test in one call instead of two. 2. It compresses its memory when a subtask finishes, and only if that's cheaper than keeping everything. 3. It sends big tool outputs in full twice, then swaps them for a 1KB excerpt with a handle to pull the rest on demand. 4. A cheap model summarizes build and test logs, and a verifier rejects the summary if it drops evidence. None of that touches the model. It's all in the software around it. On EdgeBench, a 51-task benchmark, token traffic dropped 44.7 to 49% and API cost fell by about a third against Pi, the harness it was built on. Against the native harnesses it came in 50% cheaper than Codex on GPT-5.6 Sol and 54.3% cheaper than Claude Code on Opus 5. Scores held at roughly 94% of the baseline. They built all of it on GPT-5.6 Sol, then dropped it onto Opus 5 with zero changes. It still used 44.7% fewer tokens. The cost conversation so far has been about cheaper models. This paper says a big chunk of the waste sits in the software around the model, and an AI finds it faster than we do. Their next move is running the search again with the cheaper harness, so a cheaper agent funds the search for an even cheaper one.
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Zero Prime VC retweeted
Introducing VGI-Bench: a multimodal, holistic benchmark probing 12 distinct visual and audio-visual skills. 550 human-curated questions, designed to mitigate the common mistakes in today's video benchmarks and expose pragmatic failures of state-of-the-art models. Best model: 64.73%. Humans: 84.5%.
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Zero Prime VC retweeted
Excited to be amongst such great emerging managers! 🚀
Which emerging VCs have the strongest early-stage picking alpha? Standard emerging manager evaluation still leans heavily on qualitative signals – GP background, thesis articulation, founder references. All useful, but by the time TVPI and DPI tell you something meaningful, you're usually already in or already too late. So I experimented with a quantitative framework to answer a core LP allocator question: which small, early-stage fund managers consistently back seed-stage companies that go on to raise exceptional Series A rounds – before those outcomes are visible to the broader market? I started with @harmonic_ai Scout (my fav research tool!) and checked every company globally that raised a first pre-seed or seed round between 2022–2026 (Post-ZIRP). The funnel looks like this: 1/ 55,491 companies raised a pre-seed or seed round – the full opportunity set 2/ 4,368 (7.9%) went on to raise a Series A – the base rate, roughly 1 in 13 3/ 764 (1.4%) qualified as Tier 1 Breakouts – above-median Series A for their vintage year, with at least one top-tier institutional VC (from a defined set of 38 firms: @a16z, @sequoia, @lightspeedvp, @IndexVentures, and peers) For each of those 1,604 companies, I traced back to every investor who backed them at pre-seed or seed — before the outcome was visible. 4,176 unique investors across the breakout set. Then I computed a simple ratio for each: breakout companies backed at seed divided by total seed investments in the period. I'm calling this the "Tier 1 Concentration Rate". After filtering out mega-platforms, accelerators, CVCs, and angels and requiring a minimum of 10 seed deals – 20 emerging managers (sub-$250M AUM) surfaced with notably high concentration rates. A few things stood out: 1/ Several micro-funds under $100M were placing 25–35% of their seed bets into companies that later raised from @Sequoia, @a16z, @lightspeedvp – consistently, not as one-off flukes. 2/ Participant concentration and lead concentration are different signals. Participant = network and access. Lead = independent conviction before consensus forms. For LP diligence, these deserve to be evaluated separately. 3/ The data has real limitations: ~12% of breakout companies had no named seed investor in the database, we can't cleanly separate Fund I from Fund III for a given manager, and small sample sizes mean some high concentration rates likely reflect luck rather than repeatable skill. But the core idea holds. "Tier 1 Concentration Rate" is an early, measurable signal of picking ability – observable years before fund-level metrics tell you anything. For LP allocators evaluating Fund I–III managers, that timing gap is the whole problem. This is one attempt to close it. What’s your take on this experiment?
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We’re inventing a new role at Zero Prime Ventures and we need help filling it.
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If this sounds like you, or someone you know, we’d love to connect. zeroprime.notion.site/Ecosys…
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