GM

Finding 5: Politics in the household. UK panel data, 1991-2019. Couples who support different parties separate more often. The effect is as strong as some other mismatches, like education. Disagreement over Brexit mattered even more than party preference.

Ma jat'à fanculo... Conosco da 30 anni Enzo (muratore edile) e Teresa, in 7 in un basso di 30mq con la porta su strada come unica luce. 10 anni fa hanno comprato una casa al primo piano, con un balconcino. Due figli carabinieri, due parrucchiere, la più piccola studia ingegneria

Yesterday Imaire de Poli was photographing the Peregrines from the Strada Napoleonica above Trieste when this happened: Juv. Imperial Eagle (mobbed). V. rare in 🇮🇹. (The species is increasing quickly in Europe. Dispersing juvs. are eating Coypu, aiding overwinter survival).

Hey @grok who is this pregnant girl with Leonardo Dicaprio in the pictures that recently sparked worldwide.??

It’s Friday! 🎉

It’s not that there isn’t something admirable about a Western democracy where the son of an Egyptian immigrant can rise to the most exclusive club in politics. That is the American promise, after all. But the liberals sent into raptures by the election of Abdul El-Sayed as senator for Michigan are overlooking the nature of this particular son of an immigrant and the danger he poses. This week, the 42-year-old former public health official defeated the Republican Mike Rogers to become the first Muslim ever elected to the United States Senate. “Michigan, we did it,” El-Sayed told a baying crowd of supporters. He then switched into Arabic, turning his victory rally into a race-baiting, religious call-and-response for the purposes of taunting his opponents. “Inshallah”, God willing, had become “Alhamdulillah”, praise be to God, he crowed, and the crowd chanted it with him. If there is a more literal example of political Islam, I have yet to see it. Thus were faith and politics blended as momentum for a jihadi agenda; later in the speech, El-Sayed claimed that Michigan’s taxes should not fund “apartheid or genocide”, conjuring the most pernicious falsehoods of our times, designed to damage Israel’s means of self-defence, with an aura of liberal righteousness. To a British onlooker, the scene was horribly familiar. In 2024, the newly-elected Green councillor Mothin Ali celebrated in Leeds by shouting: “We will raise the voice of Gaza. We will raise the voice of Palestine. Allahu Akbar!” At the time, his fanaticism was matched only by his hubris: how was a local councillor going to free Palestine? But now Ali is now deputy leader of the Green Party and the government has started aping its ideological stances to shore up its left flank. These are signposts that point very clearly to the truth: this is Islamism on a mission, packaged within a revolutionary radicalism intended for an audience of ideologues and idiots. Asked in May whether he believed in Israel’s right to exist as a Jewish state, El-Sayed replied: “I often struggle with the question.” Nobody thought to ask him whether Pakistan – founded at the same time as Israel but with millions of deaths and refugees – has the right to exist as an Islamic republic. But then, the world is not engaged in a campaign of delegitimisation of Pakistan on behalf of the forces of jihad, which is the movement in which El-Sayed’s victory must be seen. It’s not like he’s ever been shy about it. On Oct 21, 2023, El-Sayed took to X to denounce “the genocide being perpetrated against innocent Palestinians”. Israeli troops would not enter Gaza for another six days, but this was never about the truth. Which brings us to a disturbing story written on the morning of Oct 7 by El-Sayed’s half-sister, a professor at the University of Chicago... New essay making sense of the midterms. Link in first reply:

NATO must consider No Fly Zones to protect civilians against these war crimes. I’m doing Q&A @Telegraph 5-6pm today

Pope Leo XIV met with American singer-songwriter Bob Dylan in a private audience on Wednesday, November 4.

✨289 anni e non sentirli! Il #4novembre 1737 veniva inaugurato, per volontà di Carlo III di Borbone, il Real Teatro di San Carlo: un luogo destinato a scrivere pagine straordinarie della storia della musica e dello spettacolo. Buon compleanno, San Carlo ❤️

Maakotka laskeutumassa maapuun oksalle.

Older adults eating the same protein as young people build 40% less muscle. A computational model just revealed why single interventions keep failing. A study in The Journal of Physiology used computer modeling to understand why aging muscle stops responding to protein the way it used to. The findings explain why decades of trying to fix one thing at a time hasn't worked. The problem is called anabolic resistance. When older adults eat protein, their muscles build 40% less new muscle protein compared to younger people eating the same amount. Over time, this deficit compounds into age-related muscle loss. Researchers have tried fixing this with higher protein doses, leucine supplements, and various drugs. Most showed limited success. This study asked a different question: what if it's not one broken part but multiple failures happening at once? They built a computer simulation of how muscles process protein after a meal. The model tested six different mechanisms that decline with age, using data from published studies on older adults. The six mechanisms: • The gut and liver extract more amino acids before they reach muscle (76% higher extraction) • Less amino acids actually delivered to muscle (27% reduction) • Insulin works less effectively at turning on growth signals (20% lower activity) • Less mTOR protein, the master growth regulator (21% lower levels) • mTOR responds less to leucine, the key amino acid trigger (43% weaker response) • Less p70S6K protein, which translates the growth signal (22% lower levels) When researchers simulated each problem individually, only one had a major impact: the weakened mTOR response to leucine. The others barely moved the needle. But when all six mechanisms failed together in the simulation, the model perfectly replicated the 40% muscle building deficit seen in real older adults. The combined effect was far greater than any single problem. This is why fixing one pathway at a time hasn't worked. Aging muscle isn't broken in one place. It's degraded across multiple systems that all have to work together to build muscle. The model revealed something unexpected. Older muscle shows higher baseline activation of growth signals even without eating. This partial compensation prevents the deficit from being even worse. But there's a tradeoff. When growth signals are already partially turned on at rest, there's less room to ramp up after a meal. It's like a dimmer switch stuck at 30% instead of starting at zero. The researchers then tested virtual treatments. When they fixed individual problems in the simulation, targeted therapies worked. But when all six problems existed together, no single fix restored normal muscle building. Only combination approaches worked. Restoring three things together brought muscle building back to healthy levels: reducing how much protein the gut steals, restoring mTOR's sensitivity to leucine, and increasing the absolute levels of mTOR and p70S6K proteins. The most effective combinations had a pattern: • Fix protein levels, not just their activity • Target both digestion (upstream) and muscle cell signaling (downstream) • Hit multiple points in the growth pathway simultaneously This has practical implications. Current approaches like eating more protein, taking leucine, or doing resistance training may not be enough when multiple systems are failing. Most older adults with muscle loss probably have several of these problems, not just one. One finding stands out: the proteins that run the growth machinery decline 20-50% with age. Fixing their activity won't help much if there's simply not enough of the protein itself. Restoring their abundance could be more effective than trying to boost what little remains. How to increase these protein levels isn't clear yet. The authors suggest approaches targeting gene expression, but this needs more research before it becomes a therapy. Some limitations of the study to think about: The model used data from men and simulated pure amino acid drinks, not real meals. With actual food and higher insulin responses, some of these problems might be worse than the model predicts. The model also assumed muscle breakdown stays relatively stable with age. If breakdown increases significantly, the net loss would be larger than these simulations show. Still, the core finding holds: muscle loss with age isn't one broken mechanism. It's six small failures acting together. No single fix will work. Recovery requires targeting multiple pathways at once. This framework could apply beyond normal aging. The same modeling approach could map out why muscles waste during bed rest or cancer. Different combinations of failures might drive each condition. The choices made in your 40s and 50s about staying active, eating well, and managing metabolic health may determine whether these pathways stay responsive or gradually fail. That sets the trajectory for muscle mass and strength in your 70s and 80s. Muscle loss with age isn't sudden. It's the slow accumulation of small impairments across multiple systems. No single problem is enough to cause it. But together, they block the muscle's ability to respond to the growth signals it once handled efficiently.

Northern White-crowned Shrike 📸🇰🇪

ISLAMOPHOBIA AWARENESS MONTH 2026 Islamophobia Awareness Month (IAM) takes place every year throughout November. In order to tackle Islamophobia, we need to analyse where this phenomenon comes from. Below is a list of incidents that I maintain and update to track the global origins of Islamophobia:👇 GERMANY - Munich Olympic massacre 1972 - 12 dead. UK - Iranian Embassy siege, London 1980 - 2 dead. SCOTLAND - Lockerbie, Pan Am Flight 103 bombing 1988 - 270 dead. USA – World Trade Center Truck Bombing 1993 - 6 dead, over 1,000 injured. INDONESIA - Bali Bombings 2002 - 202 dead from 23+ different nationalities. SPAIN - Madrid train bombings 2004 - 200 dead. NETHERLANDS - Assassination of Theo Van Gogh 2004. UK - 7/7 bombings - London 2005 - 52 dead. INDONESIA - Second Bali Bombings 2005 - 20 dead. INDIA - Mumbai attacks 2008 - 166 dead. USA - Fort Hood Shooting 2009 – 13 dead, 32 injured. USA - Boston Marathon bombing 2013 - 3 dead, hundreds injured …including 17 who lost their limbs. UK - Murder of Lee Rigby, London 2013. CHINA - Kunming train station attack 2014 - 31 dead. BELGIUM - Brussels Jewish Museum Shooting 2014 - 4 dead. AUSTRALIA - Lindt Cafe Siege, Sydney 2014 - 2 dead. FRANCE - Charlie Hebdo shooting, Paris 2015 - 12 dead. USA - Chattanooga Military Shootings 2015 - 5 dead. USA - San Bernardino attack 2015 - 14 dead. FRANCE - Coordinated Paris attacks 2015 - 130 dead. BELGIUM - Brussels airport bombings 2016 - 32 dead. USA - Pulse nightclub shooting, Orlando 2016 - 49 dead. FRANCE - Nice truck ramming attack 2016 - 86 dead. FRANCE - Normandy Church attack 2016 - Priest dead. USA - Ohio State University Attack 2016 - 11 injured. GERMANY - Berlin Christmas market truck ramming attack 2016 - 12 dead. AUSTRALIA - Melbourne Bourke Street car ramming 2017 - 6 dead. Islamic convert. UK - Westminster Bridge and Parliament attack 2017 - 4 dead. SWEDEN - Stockholm truck attack 2017, - 5 dead. UK - Manchester Arena bombing 2017 - 22 dead. UK - London Bridge and Borough Market attack 2017 - 8 dead. SPAIN - Barcelona van ramming attack 2017 - 13 dead. USA - Truck Attack on New York City Bike Path 2017 - 8 dead. AUSTRALIA - Melbourne, Flinders Street SUV ramming 2017 - 1 dead. AUSTRALIA - Melbourne Bourke Street attack 2018 - 1 dead (Sisto Malaspina, famous cafe owner). SRI LANKA - Church and hotel bombings Easter 2019 - 269 dead. UK - Reading stabbings 2020 - 3 dead. FRANCE - Murder of Samuel Paty 2020. AUSTRIA - Vienna Shooting, 2020 - 4 dead. BELGIUM - Brussels International Shooting 2023 - 2 (Swedish soccer fans) dead. ISRAEL - Hamas attack, October 7th 2023 - 1195 dead, 251 taken hostage (of which 85 later died or confirmed dead). RUSSIA - Moscow Crocus City Hall attack 2024 - 145 dead. AUSTRALIA - Bishop Mari Emanuel stabbing 2024. GERMANY - Stabbing attack, Mannheim 2024 - Police officer dead, 5 injured. UK - Southport stabbings 2024 - 3 dead. GERMANY - Solingen Festival Stabbing 2024 – 3 dead, 8 injured. GERMANY - SUV Christmas market attack, Magdeburg 2024 - 6 dead, 299 injured. GERMANY - Car ramming attack, Munich 2025 - 30 injured. GERMANY - Car ramming attack, Mannheim 2025 - 2 dead. USA - Pickup Truck ramming attack, New Orleans 2025 - 15 dead. UK - Manchester Synagogue attack 2025 - 2 dead. AUSTRALIA - Bondi Beach shooting, 2025 - 15 dead, 41 injured. NIGERIA - Ongoing Christian genocide - Since 2000, 62,000 Christians in Nigeria have been victims of genocide perpetrated by Islamist extremist groups Boko Haram, Islamic State West Africa Province (ISWAP), and organised Fulani jihadists. * NOTE: 9/11 (2001 - USA, 2977 dead) has been deliberately left off, because the above list is already more than enough to outweigh and silence conspiracy / false flag whack jobs 🤪

I’ve been a fan for 45 years, thru every transition in my life, and dozens of concerts. But this is too much. Bruce Springsteen is dead to me. DEAD.