kapilpoojari

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Talk it through with Gemini now on Apple CarPlay. 🚗 Just tap the Gemini app icon on your CarPlay screen or side rail to easily pick up a conversation from your phone, explore a topic you're curious about, or brainstorm out loud with Gemini Live.

Every video starts with a story. Plan, generate, and animate your shots, all with Firefly Video. adobe.ly/48MXZzW

The secret to more replies: leave room for them. @bryan_johnson: "If you leave just the opening where they can complete the sentence, they'll pile in."

I’m very pleased to introduce AlphaGenome 2, @GoogleDeepMind’s next-generation genomics model that deciphers how DNA changes affect cells. Cells are the basic units of life and key to our understanding of biology. It is an ongoing challenge to predict how DNA changes affect the functioning of different cells, such as for a heart muscle cell or an immune cell fighting an infection, and to uncover cellular drivers of disease. To make progress on this challenge, we needed to design the architecture of AlphaGenome 2 so its predictions were conditional on cell types and states. This new design enables AlphaGenome 2 to predict variant effects across hundreds of human cell types and adapt to unseen cell and disease states without retraining. When evaluated on the TenK10K immune cell dataset, AlphaGenome 2 demonstrated a major leap in accuracy over its predecessor. It reliably identified nearly twice as many causal variants (30% vs. 16%) and directional gene effects (43% vs. 23%) compared to the original AlphaGenome. This step-change improvement in precision helps researchers pinpoint previously overlooked disease-relevant variants with high confidence. Using analysis on retrospective case studies, we were able to show AG2’s real world utility in disease understanding. A landmark study had previously shown that a variant in a distant regulatory switch drives irritable bowel disease by overactivating the ETS2 gene in gut macrophages. When used to make predictions across various immune cell types in the gut, AlphaGenome 2 singled out the exact causal variant and showed that it selectively boosts the ETS2 gene in gut macrophages, leaving other cell types and genes largely unaffected. I would like to thank my colleagues Adam Gayoso @adamgayoso, Žiga Avsec @Avsecz, and our entire genomics team for their incredible contributions and dedication to bringing this model to life. We are making AlphaGenome 2 available for non-commercial academic research via the AlphaGenome API, and soon we will release AlphaGenome 2 Skills in Google Antigravity. I’m incredibly excited to see how scientists around the world use this model to make progress on biological understanding and treating disease. Read more on our blog here: deepmind.google/blog/alphage…

I MADE 20 AI AGENTS FIGHT OVER ONE HOUSE Single-story, 1,972 sq ft, attached garage. Each agent designed the full MEP with its own strategy. Cheapest. Fastest install. Fastest hot water. Max code margin. Quietest air. 20 strategies total. Every design had to pass code first. Then the knockouts started. The "Cheapest" agent went out first. Hot water took 27 seconds to reach the tap. "Max code margin" played it so safe it went $1,200 over budget. Out. Two more drowned in clashes. 23 and 24 spots where pipes and ducts hit each other. 10 agents knocked out. 3 made the final. The winner was the most boring strategy of all: "Balanced". $11,215 in pipe, duct and wire. 252 hours of rough-in. Hot water in 5.6 seconds. 72 out of 72 code checks passed. 88,120 layouts checked to get there.

Clipping is here 🎬 Grab your favorite moment from any video, add your take, and post it without leaving X. Creators: every clip credits your original video and links back to it, so new viewers can find your work and keep watching. Clippers: you now have an easy, native way to share moments from your favorite creators directly on X. The best part? Both the original creator and the clipper can earn from views on the clip through Original Content Rewards. Everyone wins when great moments travel. Clipping is one more step toward making X the best place to create, grow and earn.

I made a full original game in 24 hours using AI Stack: Opus 5.5 + Flux 3 Max + GPT Image + Tripo + Blender + Three.js Anyone can make games now. Full workflow thread and prompt below: (1/7)