Helping people through medical cannabis education. US Navy vet (Ret), medical cannabis patient. Daily research & stories. Free newsletter ↓
Joined March 2009
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CBD calms inflammation in healthy immune cells. In MS cells? It needs THC and the right timing to work.
Whether CBD and THC can calm this early inflammatory pathway depends on when they are given and whether they are used alone or together.
In immune cells from healthy people, CBD by itself reliably dials down this inflammatory pathway.
In immune cells from people with MS, CBD alone mostly loses its effect. It only works reliably when it is combined with THC and given before the inflammatory process starts building up.
frontiersin.org/journals/imm…
Phase I Clinical Trial for Skin Diseases Using Cannabis.
OWC ran a Phase I clinical trial to test the safety and tolerability of a topical cannabis ointment for skin diseases — the first trial of its kind evaluating cannabis for clinical topical use.
The ointment is a 1:1 CBD:THC formulation (30 mg of each).
In the trial, researchers first tested a single application over 24 hours in 26 healthy volunteers, then tested repeated applications over six weeks (ointment on one arm, placebo on the other).
Results were positive.
Based on these findings, OWC plans to move forward with a Phase 2 trial of the medical-grade cannabis ointment for psoriasis.
globalcannabinoidrc.com/rese…
In a study of over 322,000 hospital patients, cannabis users had milder COVID and lower death rates!
pubmed.ncbi.nlm.nih.gov/3919…
"Cannabis administration is associated with reduced alcohol consumption"!
People drank significantly fewer drinks in the session where they used cannabis first.
These people also reported lower alcohol craving when they had used cannabis compared with when they only had alcohol.
For some people who drink heavily, cannabis may act as a substitute for alcohol.
pubmed.ncbi.nlm.nih.gov/4091…
Other studies back this up. 😎
Medical marijuana use was associated with significant improvements in PTSD symptoms, anxiety, sleep quality and overall quality of life over a two-year period, according to a new study published in the journal Psychopharmacology. themarijuanaherald.com/2026/…
For you today!
"Cannabis administration is associated with reduced alcohol consumption"!
CBD is showing REAL power against deadly glioblastoma (brain cancer)!
THC-dominant medical cannabis slashed anxiety & depression in weeks!
And more! Stay tuned!
Hopefully they’ll add medical cannabis to the mix! 😎
Microsoft's diagnostic AI solved 83% of 304 complex New England Journal of Medicine cases. Generalist physicians with reference materials solved 36%. We need to get this technology into clinics safely and fast. We need to stop making people wait for the right answers.
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CBD can reverse thinking & memory problems after traumatic brain injury!
CBD reduced damage to brain cells by lowering oxidative stress (cell damage from harmful molecules) and preventing cell death (apoptosis).
They discovered a new signaling pathway: SET / PP2A / Akt. CBD directly binds to a protein called SET.
This binding changes SET’s shape, trapping it in the cytoplasm (outside the cell nucleus). When SET stays in the cytoplasm, it blocks PP2A (which normally turns off protective signals).
This leads to activation of the Akt pathway, which protects neurons from oxidative damage and cell death, helping brain cells survive.
pubmed.ncbi.nlm.nih.gov/4151…
CBDA + CBD suppository cuts menstrual cramps by 44–68% !
Overall, average pain score dropped from 6.38 to 3.54 — a 44% reduction in pain.
Women who started with milder pain saw an even bigger improvement: from 5.43 down to 1.71 — a 68% reduction.
81% of the women ended up needing fewer oral painkillers.
academic.oup.com/jsm/article…
Medical cannabis delivers up to 2 years of real relief for migraine sufferers!
Patients showed clear improvements in headache impact, anxiety levels, sleep quality, and overall quality of life that lasted up to 2 years.
Migraine-related disability improved for up to 1 year.
Patients taking lower doses of THC (the main active part of cannabis) were also less likely to improve on migraine disability scores.
Higher doses of THC appeared to work better for reducing migraine-specific problems.
pubmed.ncbi.nlm.nih.gov/4194…
CBD supercharges colon cancer treatment!
CBD strongly turns on a group of genes called Metallothionein (MT) genes.
These MT genes are usually much lower in bowel cancer tissues than in normal tissues. Low MT levels seem to help cancer grow.
CBD reliably boosts MT gene levels.
When MT genes or zinc are increased together with CBD, it kills cancer cells even better.
pubmed.ncbi.nlm.nih.gov/3806…
People with inherited bleeding disorders use cannabis — rating it highest for sleep and anxiety!
Cannabis use was reported by people with hemophilia A, hemophilia B, von Willebrand disease, platelet disorders, and rarer bleeding disorders.
The most common reasons for using cannabis were pain, anxiety, sleep problems, and depression.
On a 0–10 scale of how well it worked, people rated it highest for sleep (about 8.4), then anxiety (about 7.1), then pain (about 6.4).
pubmed.ncbi.nlm.nih.gov/4296…
87.9% of patients reported cannabis reduced their neuropathic pain!
pubmed.ncbi.nlm.nih.gov/3818…
"Efficacy of dietary hempseed oil in patients with atopic dermatitis"
Eating hempseed oil raised levels of important healthy fats in the blood (including ones the body needs but can’t make itself, plus a skin-friendly fat called GLA).
It did not raise arachidonic acid (a fat linked to inflammation).
Skin dryness and itchiness got better.
People used less skin medication.
pubmed.ncbi.nlm.nih.gov/1601…
THC & CBD) show strong anti-tumor effects in pancreatic cancer!
They can trigger cancer cells to die (apoptosis)
They can stop cancer cells from multiplying (cell cycle arrest)
They can reduce the growth of new blood vessels that feed the tumor (anti-angiogenesis)
They can help adjust the body’s immune response around the tumor
They can lower harmful oxidative stress in cells.
ar.iiarjournals.org/content/…
CBD makes chemo work dramatically better against lung cancer!
When combined, CBD and etoposide killed lung cancer cells much more effectively than either drug alone.
The combo triggers cancer cells to self-destruct through a process called autophagy (cells basically eating themselves).
It also switches off signals that help cancer grow and spread.
aacrjournals.org/cancerres/a…
"Over 70% Of Studies Back Medical Cannabis In Cancer Treatment"
"A sweeping meta-analysis of over 10,000 studies has found that more than 70% support the use of medical cannabis in cancer treatment, reinforcing growing scientific consensus around its therapeutic potential for managing symptoms and possibly even slowing disease progression."
forbes.com/sites/dariosabagh…
Medical cannabis for chronic pain: 93% report big relief!
Daily use is common: 77.5% of patients used medical cannabis every day or almost every day.
Most popular form: Skin creams/lotions (topicals) were the most used type (63.6% of patients).
It works well for pain: Over 93% of patients said it clearly helped reduce their main symptoms.
cureus.com/articles/365077-p…
28 studies finds THC, CBD and PEA can ease chronic pain!
Palmitoylethanolamide (PEA, a cannabis-related compound) reduced pain compared with placebo.
THC alone reduced pain compared with placebo.
The THC + CBD combination improved sleep quality compared with placebo.
When broken down by pain type, CBD showed the largest pain-relief effect in cancer-related pain, while PEA performed best for non-cancer pain.
frontiersin.org/journals/pha…
