Director of bioinformatics at AstraZeneca. YouTube at chatomics. On my way to helping 1 million people learn bioinformatics. Also talks about leadership.
Boston, MA
Joined December 2011
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The guide I wish I had 12 years ago: a step-by-step guide to replicate a genomics paper figure divingintogeneticsandgenomic…
Ming "Tommy" Tang retweeted
Your drug worked perfectly in cells. Then it failed in clinical trials.
In a dish, the concentration holds steady for hours. In a person, the liver metabolizes the drug, levels drop below the effective dose, and metabolites build up in the wrong tissues.
That's DMPK.
Bioinformatics doesn’t break you with code. It breaks you with the invisible details in data. That’s where most people get lost. 🧵
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8/ Key takeaways:
Tools won’t save you if you don’t understand data.
Always ask: How was this generated? How normalized?
Read methods before trusting figures.
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Your drug worked perfectly in cells. Then it failed in clinical trials.
In a dish, the concentration holds steady for hours. In a person, the liver metabolizes the drug, levels drop below the effective dose, and metabolites build up in the wrong tissues.
That's DMPK.
1 of 290 in the field guide, and one of the 15 in the free sampler 👉 divingintogeneticsandgenomic…
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Chemotherapy enhances cancer vaccine efficacy and expands stem-like TCF1+CD8+ T cells cell.com/cancer-cell/fulltex…
Enjoy this tweet? follow me @tangming2005 and join my newsletter to learn computational biology divingintogeneticsandgenomic…
I used to be a wet lab biologist. Now I'm a bioinformatician. I started programming in year 4 of my PhD.
I felt behind. But those 4 years at the bench didn't slow me down. They gave me an edge.
Data isn't just rows and columns. It's cells, reagents, time, and luck.
Enjoy this tweet? follow me @tangming2005 and join my newsletter to learn computational biology divingintogeneticsandgenomic…
Ming "Tommy" Tang retweeted
Next week I'll be doing another FREE Concepts and Code livestream. This time we'll go through Principal Component Analysis (PCA). Register here live.statquest.org/ if you want to join the fun! BAM! :)
1 of 290 in the field guide. Free 15-lesson sampler 👉 divingintogeneticsandgenomic…
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