We study vertebrate photoreceptors
St. Louis, MO
Joined August 2021
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Corbo Lab at Washington University in St. Louis retweeted
Bryant et al. made adaptamers, <120 bp RNAs which act as regulatory elements for mRNAs so that translation only occurs in the presence of a small molecule inducer (tetracycline or doxycycline). A very clever design with lots of promise for gene therapy! cell.com/molecular-cell/full…
Corbo Lab at Washington University in St. Louis retweeted
A pair of studies analysing more than 4,700 ancient human genomes has identified the possible origins of Celtic and Germanic languages
go.nature.com/4z4lG1s
Corbo Lab at Washington University in St. Louis retweeted
Miniaturização coincide com novidades anatômicas durante as origens dos Lissamphibia academic.oup.com/nsr/advance…
Corbo Lab at Washington University in St. Louis retweeted
I am very pleased to announce that my paper, which details a new evolutionary theory on how allometric traits evolve is now out in The Evolutionary Journal of the Linnean Society. Link:
academic.oup.com/evolinnean/…
Corbo Lab at Washington University in St. Louis retweeted
Researchers in @ScienceAdvances have demonstrated that brief physical contact between healthy and bleached coral can restore algae to the bleached coral, leading to their full recovery. scim.ag/4s40Tt3
Corbo Lab at Washington University in St. Louis retweeted
Kerp, H., Bomfleur, B. & Krings, M. The Rhynie chert Lagerstätte – An Early Devonian hot-spring ecosystem frozen in time. PalZ (2026). doi.org/10.1007/s12542-026-0…
Corbo Lab at Washington University in St. Louis retweeted
🚨 Our new paper is out in @iScience_CP! 🐟
3D morphometrics, CFD & Pareto optimality reveal high-performing designs that early vertebrates never evolved—challenging models of evolutionary constraint.
@Macro_Fun @BristolPalaeo @CellPressNews
🔗 sciencedirect.com/science/ar…
Corbo Lab at Washington University in St. Louis retweeted
Are deep-sea fishes truly circumglobal? This new study reports extensive cryptic (hidden) diversity in the Sternoptyx and Argyropelecus across the abyssal plains worldwide, with divergence time of tens of millions of years.
researchgate.net/publication…
Welcome back. Lots of science still here! Check this out: The role of abiotic and biotic factors in the unequal body shape diversification of a Gondwanan fish radiation.
researchgate.net/publication…
Corbo Lab at Washington University in St. Louis retweeted
Museum Resource 🐠 Fish Families of the World Gallery
📌 This gallery of museum vouchered specimens is designed to support instructors in need of teaching materials.
Browse: floridamuseum.ufl.edu/discov…
Searchable gallery includes photos, CT scans, 3D models, x-rays & more!
ALT a screenshot of a list of several kinds of fish with their scientific and common family name below each image of a preserved fish specimen including a jack, codlet, catfish and flounder
Corbo Lab at Washington University in St. Louis retweeted
A supergene and genomic mosaicism are associated with phenotypic evolution in Galápagos tree finches nature.com/articles/s41467-0… @NatureComms
Corbo Lab at Washington University in St. Louis retweeted
Our new paper @CellReports, led by @katsu_s_minami et al.! 🎉🧬🔬
cell.com/cell-reports/fullte…
Machine learning-assisted Repli-Histo labeling and single-nucleosome imaging reveal distinct transcription-dependent chromatin constraints across euchromatin and heterochromatin. Congrats!
Corbo Lab at Washington University in St. Louis retweeted
Amphibians were able to live in the sea 237 million years ago, according to new research
go.nature.com/4zkZcKz
Corbo Lab at Washington University in St. Louis retweeted
Biologists saying AI doesn't offer much to biomedicine might sound like hubris, but it's more of an embarrassing confession about how important we think our intelligence is to progress in biomedicine (as opposed to plain luck and elbow grease). 1/10
Corbo Lab at Washington University in St. Louis retweeted
真核生物に最も近縁なアスガルド古細菌から見つかった祖先系の微小管
ヘイミダル古細菌から見つかったAtubA/Bというタンパク質であり、GTP依存的にヘテロダイマーが重合し、シームを持ち動的不安定性を示す4本鎖の繊維を形成していた #BNTNJC
science.org/doi/10.1126/scia…
Corbo Lab at Washington University in St. Louis retweeted
"Climatic niche conservatism istherefore ancient in crocodile-line archosaurs, but not completely static."
I like this "evolution through temperature space" phylogram aesthetic.
CC: @svalver
Climatic niche conservatism shapes the macroevolution, extinction, and survivorship of crocodile-line archosaurs | Science Advances science.org/doi/10.1126/scia…
Corbo Lab at Washington University in St. Louis retweeted
What if you could see light in a whole new way?
Michael Shribak (@mshribak), a senior scientist at the MBL, developed and patented a polychromatic polarization microscope that allows him to visualize an "invisible" property of light.
🔗 Read more here: go.mbl.edu/light
Corbo Lab at Washington University in St. Louis retweeted
Regulatable in vivo gene expression via adaptamers sciencedirect.com/science/ar…
Corbo Lab at Washington University in St. Louis retweeted
Just out: some fish 🐟 lost their green opsins but evolved a functional alternative from duplicated red (LWS) opsins — much like the evolution of red-green vision in primates! 🔴🟢 Different lineages, similar evolutionary solutions! Go red opsins! Go gobies! Thks co-authors🤗
Corbo Lab at Washington University in St. Louis retweeted
🧬🌊 New preprint from our lab: DO1 Cas9, the first Cas9 nuclease characterised from the deep ocean — recovered from a metagenome at 1,500 m in the Atlantic.
❄️Cold-adapted: it cuts DNA efficiently at low temperature, where mesophilic SpCas9 retains only residual activity. 🧵1/4
Corbo Lab at Washington University in St. Louis retweeted
It seems to me that this paper fundamentally rewrites the standard "textbook" story of human evolution in three major ways:
(1) The idea of a "pure" modern human origin in Africa is destroyed because every human alive today would be the result of a massive genetic "remixing" of ancient lineages occurring mostly outside Africa — lineages that had previously been separated for over a million years.
(2) Neandertals are not a separate parallel branch of humanity, but rather essentially a hybrid population of early humans expanding into Europe 300,000 years ago and mixing heavily with them.
(3) The previous timeline of the Out of Africa theory is significantly pushed back by a "bicontinental range expansion" that occurred 300,000 years ago.
New David Reich preprint proposes the expansion of early modern humans into Europe 300,000 years ago, likely originating from the Near East and/or Northeast Africa — long before the migrations about 50,000 years ago posited by the Out of Africa theory.
biorxiv.org/content/10.64898…