Professor scientist, immunologist, biomedical engineer & Biohacker. ALL IN ON AI, SI & ROBOTICS! #Longevity #BioAI #Codex #Space #Scifi #Singularity #trekkie 🖖
Connecticut, USA
Joined February 2020
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It’s a bit surreal to see myself on a billboard in San Francisco!🫣
My deepest gratitude to @OpenAI for choosing me to represent one of the millions of creative ways people use Codex.
What an incredible honor to be part of this small moment in the history of the age of AI!
Wow! Google is now better than Jev on most decision benchmarks! In particular, Gemini Decisions have video decision-making, that's a very big deal!
I said this multiple times: In the age of AI don’t bet against Google!
Today we’re launching the Gemini Decisions API, powered by our new Gemini Decision 1 model in @GoogleAIStudio.
Instead of generating text token by token, it’s built for closed-set choices scoring up to 1,000 questions across text, images, audio, video + PDFs in a single pass. A few details:
- 3 decision types: yes/no, multiple choice (up to 255 options) + rubric scoring
- $0.10 / 1M input tokens with $0 billed for output tokens (~5x cheaper than Flash-Lite)
- leads on several benchmark evals with lowest calibration error
Google teams are already building with it, below is a look at Stitch Rapid designing a full product flow in seconds (1x speed)
Super cool! AlphaGenome 2 just landed! This is one of the critical BioAI models for identifying the genetic basis of disease & even aging!
It’s all about our biocode (DNA). Once AI has a complete handle on that, we can fix it, rewrite it, and engineer it from a clean slate!
Super proud to announce AlphaGenome 2 - our new DNA sequence model! 🧬 It predicts the impact of DNA variants in different specific cell types - unlocking crucial information for understanding complex diseases. Available for academic research via our API: alphagenomedocs.com/
This is no joking matter. Millions of people are suffering and dying, and every single day counts.
Dario is absolutely right about this, and I support him 100%!
“LinkedIn” doesn’t seem very linked in to the AI tsunami that’s coming! 😅
It’s the social network of gatekeepers and status quo defenders, and they have the most to lose from the AI revolution!
🤯The era of Science 4.0 has begun for math and physics, as AI solves most problems and makes new discoveries! Congrats to @OpenAI on another monumental achievement with their AI models! 👏🚀
“Initial assessment. This validation covers the first OpenAI Lean submission, which formalizes the continuum pure Yang-Mills theory. In our judgment, the submission proves that a relativistic quantum field theory satisfying the Wightman axioms can be constructed as a scaling limit of four-dimensional Wilson lattice gauge theory for any simple compact gauge group. It does not prove that the infinite-volume limit is unique or that there is a mass gap.”
[Yang-Mills Working Group]
Validation of the OpenAI Yang–Mills construction
(November 10, 2026)
OpenAI-YM-20261028: github.com/yang-mills-group/…
github.com/yang-mills-group/…
As a tribute to @demishassabis, I rebuilt his iconic 1994 Theme Park game, with Gemini 4 Carbon in HD pixel art in 36 minutes, one-shot just from a video link of the original game! I am amazed at how good this model is! You can also play it here : theme-park-hd.vercel.app 🎡🎢
I asked Fable 5.2 for a film about the life of a T cell, immune cells I study. It wrote the script, fact-checked the immunology, built every cell in Blender, rendered 12,480 frames & added the narration & score!
I am stunned by the beauty of this 8 minutes 40 seconds video!🥹😍
The narration audio here was generated with @ElevenLabs via @higgsfield
MCP, works really well with Claude, recommend it.
💯 AI is the greatest threat to authoritarians, gatekeepers, & those who cling to power & privilege by controlling our lives. From math & science to healthcare, education, & governance, AI has the potential to disrupt every entrenched power structure.
Unless, of course, they are the only ones who control AI itself.
We must never allow that dystopia to become our future!
one of the most revolutionary things about AI is that it threatens the foundations of authoritarianism
it's an existential threat to anyone whose power depends on keeping other people ignorant and incapable of thinking for themselves
so whenever a politician says that we need to stop AI progress "until we can control it", believe them
Fantastic BioAI model from @QuanquanGu and his team. Tried it and generated the TNF homotrimer structure, easy to use and fast!
Introducing NovaAtom-Lite, an all-atom structure prediction model for drug discovery.
It predicts the structures of proteins, nucleic acids, and the molecules they bind, including how they fit together.
NovaAtom-Lite outperforms both IsoDDE and AlphaFold 3 on FoldBench antibody–antigen structure prediction (DockQ ≥ 0.23):
NovaAtom-Lite: 79.07% (n=172)
IsoDDE: 75.58%
AlphaFold 3: 47.90% (n=167)
Our evaluation uses 5 seeds × 5 samples, with the top-1 prediction selected by the model's own ranking score.
Better structure prediction. A stronger starting point for your next experiment.
Live today via Geodesic API and NovaDDE.
🔗 API: platform.geodesiclab.com/
🔗 NovaDDE: agent.geodesiclab.com
🔗 Model Card: geodesiclab.com/news/introdu…
Woohoo! Just got access to Gemini 4 Carbon!
Let the testing and playing begin!
Gemini 4 Carbon is rolling out today. It’s built for sustained, long-horizon tasks, reasoning deeply through complex software engineering, cybersecurity, and scientific discovery.
Coming globally via the Gemini API in @GoogleAIStudio and Gemini for business, and for Ultra subscribers in @antigravity, the @GeminiApp, and AI Mode in Search.
The age of super intelligence and Singularity is coming next year!
2027 will be a turning point year in human history, civilization is about to jump to an unimaginable level and very very few people comprehend or realize what’s still is coming!
I've summarized where things stand at the AI frontier:
- Unreleased models (Anthropic's Models 3 and 4) are now half-way between AI2027's Agents-1 and 2 (graphs fixed for the bug flagged by the AI2027 authors). @DKokotajlo please let me know if I missed something.
- We're right on track with AI2027's prediction of an automated coder (AC) for April 2027, wild. Public models are now massively lagging unreleased models (1 day vs. 1 week of autonomous high-quality work). Fuelled by RSI, the gap is huge and growing.
- This trajectory, if continued, means a world-changing intelligence explosion in 2027, so the public needs to know. I highly recommend reading more on the topic to grasp what's coming.
AI agents helping with longevity is very cool!
“Longevity Grok is a team of AI agents on Grok Bot, led by PLSI, your Personal Longevity Superintelligence. It keeps your labs, wearables and plans in one place, researches the questions that matter to your goals, and prepares your visits with physicians you already trust. If you choose, it can also help the whole field learn faster.”
🧬 What if you could make a prediction about your health and then check how accurate it was?
Longevity Grok, developed by Insilico Medicine with @davidasinclair’s lab, brings together a team of agents on @bot to help you explore your health data and longevity research. It can create prediction cards for biomarkers and compare them with future measurements.
An exciting step toward more personalized, evidence-driven longevity research. 🔬
Try it here: longevitygrok.si
At 09:05 this morning the republic of Turkiye stood still, to remember its founder Mustafa Kemal Atatürk, as it has every 10 November for 88 years.
He created a modern republic from the ashes of an empire.
1881 – 193∞
With reverence, gratitude & longing.
Video by Fable 5.2
Incredible post from Matthew testing Fable 5.2. He's spent over 100 billion tokens, and the examples are breathtaking!
I still remember early 2025, when his best AI demos were Snake and Tetris games. AI advanced a bit in the last two years😅
Fable 5.2 is HERE! 🔥
I've burned over 100 billion tokens early testing Fable 5.2. It is BY FAR the best model I've ever used.
Here's my full review (including Gears of War clone):
> Fable 5.2 is the most autonomous model to date. Given a task with little direction, it makes assumptions that 99 times out of 100 are exactly what I would have done.
> It's a bug catching genius. I tasked it with going over all of my codebases and it found bugs that no other model would have found.
> It is the most capable model I've used with 3D generation. It is so good at controlling Unreal Engine and Blender. Check out my Gears of War clone attached.
> It's SUPER fast. I wasn't even using fast mode. It's less about how fast the tokens per second are, it's more about how it figures out direct paths to solutions. It doesn't get lost, it just knows exactly what it needs to do.
> And then there's Ultracode...which is ridiculously fast for massive tasks. I gave it massive codebase review tasks and it would finish in 10-20 minutes, finding every possible issue. I probably won't be using it as it'll burn my sub quota too quickly.
> Fable 5.2's completeness of work continued to surprise me. Clone Excel? Done...with full feature parity. Clone Gears of War? Done. Build a replica of Tokyo in Unreal? An entire simulated city is born. I rarely had to send follow up prompts to get it to complete something.
Now, will I use it over Opus 5.5? I will likely still prefer Opus because I can run Opus nearly 24/7 and rarely run out of quota. And for the hardest jobs, I'll switch to Fable 5.2 for planning.
Wow, just WOW! 😲 This video from Fable 5.2 gave me chills! Absolutely mind-blowing!
It feels like we’re witnessing a glimpse of the superintelligence era unfolding before our very eyes!
The future is arriving faster than we ever imagined, and it’s breathtaking! 🚀🫨
I can confirm this AI sentiment is true in Turkey; enthusiasm for using AI is much higher than what I see in the US. People see AI as a massive opportunity to catch up with technology, expertise & improve their quality of life, whereas in the West it is maintaining the status quo
But do they have the permission of mathematicians and physicists from Princeton and the IAS? They need to approve whether you can make these revolutions in San Francisco or elsewhere with AI and give their blessings! 😅
