Pawel K. Mazur (@MazurLab) header
Pawel K. Mazur (@MazurLab) profile picture

Pawel K. Mazur

@MazurLab

Associate Professor, MD Anderson Cancer Center. We are dedicated to identifying novel therapies for lung and pancreatic cancer. Join our team! #mazurforthecure

 Houston, TX
mdanderson.org/mazurlab
Joined July 2009
  • Tweets241
  • Following222
  • Followers394
25Media
Photo by Pawel K. Mazur (@MazurLab)Photo by Pawel K. Mazur (@MazurLab)Photo by Pawel K. Mazur (@MazurLab)Photo by Pawel K. Mazur (@MazurLab)Photo by Pawel K. Mazur (@MazurLab)Photo by Pawel K. Mazur (@MazurLab)Photo by Pawel K. Mazur (@MazurLab)Photo by Pawel K. Mazur (@MazurLab)Photo by Pawel K. Mazur (@MazurLab)Photo by Pawel K. Mazur (@MazurLab)
The MazurLab @MDAndersonNews was walking at the #PanCANPurpleStride #PurpleStrideHouston today to raise awareness for this devastating disease and show support for pancreatic cancer survivors @PanCAN @PancanHouston
Image from Simone Hausmann (@Simone_Hausmann)
Image from Simone Hausmann (@Simone_Hausmann)
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The @MazurLab met early this morning to support pancreatic cancer research at #PanCANPurpleStride in Houston
Image from Simone Hausmann (@Simone_Hausmann)
Image from Simone Hausmann (@Simone_Hausmann)
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Pawel K. Mazur retweeted
Julien Sage (@SageJulien) profile picture
Julien Sage@SageJulien14 Apr 2021
Excited about this publication from star student Andrea Chaikovsky @stanfordcbio on the regulation of Cyclin D levels and the response to Cdk4/6 inhibitors. Close collaboration with many labs, including @LabWinslow, @PetrovADmitri, @cncurtis, @KroganLab... rdcu.be/ciGW3
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Pawel K. Mazur retweeted
Cancer Discovery (@CD_AACR) profile picture
Cancer Discovery@CD_AACR18 Feb 2021
#ResearchWatch: The histone methyltransferase NSD3 is a lung squamous cell carcinoma driver. @MazurLab @MDAndersonNews @Stanford #LungCancer #Epigenetics bit.ly/3qxsTov
Image from Cancer Discovery (@CD_AACR)
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NEW #ResearchHighlight! Research by the teams of Shao, Jaremko, Mazur @MazurLab & Gozani shows that NSD3, which encodes a histone H3 lysine 36 methyltransferase, is likely an important driver of a subset of lung squamous cell carcinomas. 📯 go.nature.com/3qMIgcJ @NatResCancer
Image from Nature Reviews Cancer (@NatureRevCancer)
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Pawel K. Mazur retweeted
EpiCypher, Inc. (@epicypher) profile picture
EpiCypher, Inc.@epicypher4 Feb 2021
New work from Or Gozani @MazurLab and co. finds that a mutated form of NSD3 results in increased H3K36 methylation and promotes lung cancer development. Also used EpiCypher's pAG-MNase for CUT&RUN assays and our nucleosomes for HMT experiments! #chromatin nature.com/articles/s41586-0…
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Pawel K. Mazur retweeted
PubMed Trending (@PubTrend) profile picture
PubMed Trending@PubTrend9 Feb 2021
Trending on PubMed: Elevated NSD3 histone methylation activity drives squamous cell lung cancer. pubmed.ncbi.nlm.nih.gov/3353…
Elevated NSD3 histone methylation activity drives squamous cell lung cancer - PubMed

Elevated NSD3 histone methylation activity drives squamous cell lung cancer - PubMed

Amplification of chromosomal region 8p11-12 is a common genetic alteration that has been implicated in the aetiology of lung squamous cell carcinoma (LUSC)1-3. The FGFR1 gene is the main candidate...

pubmed.ncbi.nlm.nih.gov
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Pawel K. Mazur retweeted
FrezzaLab (@FrezzaLab) profile picture
FrezzaLab@FrezzaLab3 Feb 2021
Elevated NSD3 histone methylation activity drives squamous cell lung cancer | Nature nature.com/articles/s41586-0…
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Hyperactivity of the methyltransferase protein NSD3 drives some cancers go.nature.com/3rd90Tw
Image from Nature News & Views (@NatureNV)
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Researchers at @Stanford, @MDAndersonNews, @KAUST_News & @UM_1981 showed that elevated NSD3 histone methylation activity drives squamous cell #LungCancer. 📌 @nature 🔗 go.nature.com/3oKFNgV
Image from Pulmonary Cell News (@pulmonary_news)
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The discovery that methyltransferase protein NSD3 drives some cancers opens up new therapeutic opportunities go.nature.com/3rd90Tw
Image from Nature News & Views (@NatureNV)
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Hyperactivity of the methyltransferase protein NSD3 drives some cancers go.nature.com/3rd90Tw
Image from Nature News & Views (@NatureNV)
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Pawel K. Mazur retweeted
Cancer Cell (@Cancer_Cell) profile picture
Cancer Cell@Cancer_Cell9 Jun 2020
SETD5-Coordinated Chromatin Reprogramming Regulates Adaptive Resistance to Targeted Pancreatic Cancer Therapy dlvr.it/RYJZSK
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Scientists from @MDAndersonNews identify SETD5 as a major driver of pancreatic ductal adenocarcinoma resistance to MEK1/2 inhibition. Published in @Cancer_Cell: bit.ly/2Utug9v
Image from Pancreatic Cell News (@PancreaticCell)
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Pawel K. Mazur retweeted
Julien Sage (@SageJulien) profile picture
Julien Sage@SageJulien25 May 2020
Congratulations to @MazurLab and collaborators, including the Gozani lab, for their beautiful work on Setd5 and resistance to treatment in pancreatic cancer. Excited to finally publish with @Aiims1742! sciencedirect.com/science/ar…
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I'm pretty tired of hearing how we scientists are supposed to be so productive now. Anyone with kids, elderly parents, lab members to worry about, stranded masters students, etc is too stressed and busy to be thinking big thoughts.
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Pawel K. Mazur retweeted
Julien Sage (@SageJulien) profile picture
Julien Sage@SageJulien10 Jan 2020
Lots of good news, including in lung cancer in general, but still a flat survival for SCLC sadly
Image from Julien Sage (@SageJulien)
Julien Sage (@SageJulien) profile pictureJulien Sage@SageJulien10 Jan 2020
Excited to have @NCIDirector Ned Sharpless with us today. Looking forward to his talk, thanks @SCIDirector for inviting him!
Image from Julien Sage (@SageJulien)
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SCI member Crystal Mackall and colleagues modified #CARTcells to remain active in mice even under conditions that would normally result in their exhaustion - important implications for developing the next generation of #cancer #immunotherapy treatments. stan.md/2PjONKy
Image from Steven Artandi, MD, PhD (@SCIDirector)
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Pawel K. Mazur retweeted
Julien Sage (@SageJulien) profile picture
Julien Sage@SageJulien10 Mar 2020
Excited to share our review with @TuomasTammela, who is a true master of both tumor heterogeneity and mouse models @AnnualReviews annualreviews.org/doi/abs/10…
Image from Julien Sage (@SageJulien)
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Pawel K. Mazur retweeted
Anirban Maitra (@Aiims1742) profile picture
Anirban Maitra@Aiims174212 Nov 2019
Doug Hanahan in @PNASNews on deregulated MicroRNAs in pancreatic #Neuroendocrine tumors. A new algorithm (Bio-miRTa) is described for identifying functionally relevant gene targets of MicroRNAs. pnas.org/content/early/2019/…
Image from Anirban Maitra (@Aiims1742)
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