Precigenetics

I don't think AI can cure cancer until it has the right data to learn from. Right now, that data mostly doesn't exist. I believe Precigenetics can change that. Most large biological datasets used to train AI "virtual cell" models show cells at a single moment, usually because the measurement (ex: sequencing) destroys the cell. You get a "before" and an "after" treatment, but not the path in between. That path can matter a lot though. For example, tumor cells adapt to drugs over hours and days, and resistance often emerges in exactly the window a snapshot misses. Precigenetics addresses this challenge by measuring the dynamic response of cells to drugs and other perturbations. They can measure morphological and biochemical changes inside living cells, without labels or killing the cell. The second problem is that most of this kind of data comes from 2D cell lines or animal models, which often don't represent how human tissue will respond. That's one reason so many drugs that look promising in preclinical studies fail in human trials. Precigenetics is extending its platform to human organoids, 3D tissue models that more closely resemble real human biology. Put those together and you get exactly the kind of data that is needed to train the next generation of AI virtual cells to solve cancer (and other diseases!). Parmita is a formidable founder and she is now looking for investors to support her mission. If you are an angel investor, I highly recommend reaching out! Full disclosure: I am an advisor for, and hold equity in Precigenetics.

If I had $1B I would build in noninvasive biotech devices. Microscopes. Shine some waves on your cells to understand what state they’re in at multiple time points

Please repost this for reach. We are soon going to be looking for a chief of staff (CoS) for Precigenetics!!! Email parm@precigenetics.com We will have a hiring page launch at Precigenetics dot com slash careers for other roles like -head of automation (robotics and factory scale/biomanufacturing expertise): sasaan@precigenetics.com -executive assistant, primarily for my schedule: parm@precigenetics.com -business dev lead: Pharma: parm@precigenetics.com , aru@precigenetics.com -business dev lead: AI: parm@precigenetics.com, aru@precigenetics.com -CSO (looking for professors and other people right out of the industry): parm@precigenetics.com -wet lab biologist, complex cell culture: aru@precigenetics.com, parm@precigenetics.com -biologist, toxicology (hepatotox): aru@precigenetics.com, parm@precigenetics.com You can also dm at @arubikscube , @parmita , @SasaanAShowghi , and soon will be opening DMs on @Precigenetics For any other info, email admin@precigenetics.com

Tycho is our industrialized effort. What the space is to a James Webb Space Telescope, life is to Tycho.

I'm so far into Tpot that last night I had a dream @bryan_johnson was in the hospital and being treated by @parmita who was doing some modification on his body and when she walked off they brought him a tray of food. It had peach rings and gummy worms and chicken and he started lecturing the staff on how they were serving sick people poison 😭😭😭😭 I told him I'd go grab apples but he decided not to have one because they weren't organic. Idk idk idk it might have just been a nearby reality and not a dream.

AlphaFold is a throughput optimization on drug discovery, not a latency optimization. You still need to go through phase 1/2/3 clinical trials, but the number of drugs that enter clinical trials + pass all of them increases

We are making great progress here in AZ. So excited to show you all what we are building here!

Arizona Secures Critical American Biofactory Hard Tech Headlines: - @regentcraft, the American seaglider startup, has successfully demonstrated its autonomous seaglider at Silent Swarm. It is the first defense-specific wing-in-ground-effect craft in U.S. history. - @Textron has secured a $230M+ deal with the U.S. Navy for two Ship-to-Shore Connectors, amphibious hovercraft designed to move troops, vehicles, and supplies from ships offshore directly onto beaches. - @Precigenetics, the startup developing real-time living-cell imaging technology, is expanding to a new biofactory in Arizona, where it plans to manufacture critical biohardware in the U.S. - @smackaistack has secured a $61M Series B led by Costanoa Ventures. Smack is developing a frontier AI lab for defense, enabling autonomy decisions to be made at the campaign level. The startup is using the funding to develop custom hardware to deploy its models on-prem. - @EdgeRunnerAI, in partnership with the U.S. Army’s AI2C, has introduced a new military-focused large language model that reduced error rates by 37% across Army-specific tasks and is designed to run locally at the tactical edge. - Grounded has raised a $5M seed round. The Detroit startup develops software-defined, modular commercial electric vehicles and is expanding production into a new 50,000-square-foot facility. - Eoptic, Inc., the advanced imaging firm, has secured a deal to supply multiple payloads for strategic space imaging programs, with first deliveries planned for early 2027. - @AerogenSystems has launched out of Y Combinator, developing self-cleaning infrastructure for semiconductor manufacturing that creates ultra-clean environments around wafers. - @saildrone has opened a European HQ in Copenhagen and is expanding USV production in Europe, including its next-generation Surveyor at Umoe Mandal’s facility in Norway. - Skanska and Stacy Witbeck secured a $2.43B contract to expand LA Metro’s rail infrastructure in the San Fernando Valley. - Einride is purchasing 500 Tesla Semi trucks, the largest Tesla Semi order in history. - The U.S. Army has awarded @elroyair $46M to advance autonomous heavy-lift aircraft for moving cargo across contested environments. The VTOL can carry 500+ pounds of cargo, fly up to 450 miles, and operate without runways in austere environments. - @valinortech announced HarborPOD, designed to turn autonomous systems into casualty evacuation or resupply platforms. We break it down in today’s Hard Tech Headlines video.

My grandma was reading the newspaper and then she found me there @timesofindia omg

.@Precigenetics unofficial jingle

.@Precigenetics unofficial jingle