Posts are my own immediate personal reflections on current events or views expressed by others. Retired. Professor, Translational and Functional Genomics.
La Jolla, CA
Joined July 2015
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Blood-based RNA biomarker for the early detection of ovarian cancer.
nature.com/articles/s41591-0… – at San Diego, CA
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This is great conversation, Lex! Thank you for doing this job and thank you for sharing. – at San Diego, CA
Here's my conversation all about the state of the war in Ukraine with Preston Stewart (@prestonstew_) and Michael Kofman (@KofmanMichael).
It's here on X in full and is up everywhere else (see comment).
Timestamps:
0:00 - Introduction
1:00 - State of the war in Ukraine
14:39 - Drone warfare and the kill zone
51:49 - Who is winning the war?
1:03:26 - Military analysis of Russia's 2022 invasion
1:19:14 - Battle of Bakhmut
1:34:56 - War optimism and bad information
1:55:05 - Prigozhin's mutiny
2:09:20 - Putin vs Zelenskyy
2:27:18 - Trump
2:36:13 - Paths to peace in Ukraine
2:46:53 - Nature of war
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If only some of these predictions would come true, it would be remarkable. The objectives themselves are not compatible with the clinical science logic: one cannot prove the cure of cancer or Amlzheimer's within few years time period even if the RCTs were yo start today. – at San Diego, CA
Very important observations. Will help many people. – at San Diego, CA
The impressive impact of strength training for preserving muscle mass while taking a GLP-1 drug for obesity, as seen in randomized trial @NatureMedicine
T=tirzepatide alone (Zepbound), T + REx=drug with resistance exercise
nature.com/articles/s41591-0…
Resistance exercise to attenuate lean mass loss during tirzepatide therapy for obesity: a randomized controlled trial.
nature.com/articles/s41591-0… – at San Diego, CA
Ethan Mollick on AI: Where Are We Now and Where Are We Headed.
erictopol.substack.com/p/eth… – at San Diego, CA
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Some people are resistant to dementia — here’s what their genes can teach us.
Researchers have studied people with a genetic predisposition to Alzheimer’s and other dementias. They might have even more to learn from those who don’t get the disease.
nature.com/articles/d41586-0… – at San Diego, CA
Fascinating study. Thank you for sharing. – at San Diego, CA
What can we learn from how people walk?
We filmed over 3,000 people, extracted 3D skeletons, and trained a gait foundation model. Movement predicted BMI, visceral fat, age and 1,887 traits from grip strength to sleep
Our new @NatureMedicine paper: nature.com/articles/s41591-0…
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A gait foundation model for prediction of multisystem health phenotypes from 3D skeletal motion.
nature.com/articles/s41591-0… – at San Diego, CA
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I hope and wish you will be able to keep this desire and commitment for the rest of you life. If you will, you will make many people happy. – at San Diego, CA
From 30 years ago , me as a little kid in Bulgaria. Second entry of my diary. I found my purpose and it’s “to make people happy” 🥹🫶❤️. It’s not to win a prize, it’s not be rich or famous, or a successful scientist. Just to help people find happiness.
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Seven ways not to think carefully about aging.
link.springer.com/article/10… – at San Diego, CA
Discontinuing Statins in Older Adults without Cardiovascular Disease | New England Journal of Medicine nejm.org/doi/full/10.1056/NE… – at San Diego, CA
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Human whole-blood NAD+ levels do not vary with age or lifestyle interventions.
nature.com/articles/s42255-0… – at San Diego, CA
Intensive Blood-Pressure Lowering in Patients with Type 2 Diabetes | New England Journal of Medicine nejm.org/doi/full/10.1056/NE… – at San Diego, CA
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Intensive Blood-Pressure Lowering in Patients with Type 2 Diabetes | New England Journal of Medicine nejm.org/doi/full/10.1056/NE… – at San Diego, CA
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Programming immunity in situ: A new frontier of in vivo cell engineering | Science Immunology science.org/doi/10.1126/scii… – at San Diego, CA
It is not enough just yo say it. We will have to make it happen. – at San Diego, CA
🚨🇵🇱 For those of you across the Ocean, this is Kraków, Poland 🕯️
To everyone who took our happiness away
Who plunged Europe into this chaos
With every breath in my body and every ounce of strength I have:
F… OFF!!!
And when you get there, F… OFF AGAIN
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