A new way to measure how AI agents handle the routine analyses of wet-lab science—BioBasicsBench.
Developed with Ligo, a biotech company focused on enzyme design, the benchmark draws on 100 tasks from real experiments to test whether agents can interpret raw lab data, identify errors, and recognize when the evidence doesn’t support a conclusion.
Accelerating biological research starts with getting the everyday work right. BioBasicsBench shows where models need to improve, and helps us track what those gains mean for scientific progress, biosafety, and biosecurity.
openai.com/index/measuring-h…
Joy Jiao retweeted
Thanks @gdb for supporting @perturbai_tx from the beginning and connecting us with @joyjiao12 and her amazing team at @OpenAI.
Joy Jiao retweeted
💥 Introducing Warp Sciences, a new company applying AI and robotics to help the world develop new medicines faster.
We’ve raised a $215M Series A led by @lightspeedvp to bring frontier AI out of the browser and into the lab, and build scientific capacity here in America.
I co-founded Warp with my long-time friend @dpatil, FAIR co-founder @manohar_paluri, and drug hunter Sol Reisberg. The early team is full of incredible people like @bkspears9, who helped achieve Q>1 fusion at LLNL.
Joy Jiao retweeted
At @OpenAI we are hiring a Life Sciences Partnerships Lead to shape and execute OpenAI’s global life sciences partnership strategy. You will lead high-impact research, product, and platform partnerships across the life sciences ecosystem. Learn more and apply at
openai.com/careers/business-…
Joy Jiao retweeted
Discovery often comes from putting familiar pieces in unexpected ways: but bio space is too vast to do that effectively?
🤖 1000s of AI agents helped connect our whole-brain Perturb-seq atlas w literature. w @OpenAI @joyjiao12: more coming! See preprint biorxiv.org/content/10.64898…
GPT-Rosalind surfaced a new lead for drug discovery: could restoring cholesterol transport protect neurons from degeneration?
DCTN1 is a gene linked to Perry syndrome, a rare neurodegenerative disorder. In mouse-brain data, disrupting it increased expression of genes involved in making cholesterol. GPT-Rosalind suggested a possible explanation: cholesterol may not be reaching where neurons need it.
That gives scientists a specific mechanism to test and, if confirmed, a direction for developing new treatments for neurodegenerative disorders.
With @perturbai_tx and @scrippsresearch, a team of thousands of GPT-Rosalind agents worked in parallel, connecting gene-expression results from millions of mouse brain cells with scientific literature in just 32 minutes. We’re now expanding this collaboration to identify new drug targets.
openai.com/index/scaling-ai-…
Very excited to build together!
We’ve acquired Orchestra Bio, a platform that helps biopharma teams coordinate the complex process of drug development.
Together, we’ll build on Rosalind, our AI models and tools for life sciences research, to streamline those operations and help new treatments reach patients sooner.
Welcome @ashokaraj_ and team!
openai.com/index/openai-to-a…
We're expanding access to GPT-Rosalind for academic research.
The new Rosalind Academic Plan helps scientific labs bring AI into the work of understanding biology, exploring ideas, and deciding what to test next—with sponsored access for eligible labs at U.S. universities.
Academic research starts with questions whose impact may take years to impact human health.
Joy Jiao retweeted
Scientific research is scattered. @OpenAI's Rosalind Workbench allows life science researchers to analyze data, inspect evidence, and review outputs in one place.
tinyurl.com/2b4c4jwp
Joy Jiao retweeted
The Rosalind Workbench has been out for a week now - show me the coolest thing you've built with it!
Coolest project gets 1 free year of ChatGPT Pro!
Either comment here or quote tweet me to submit. Provide screenshots and the Rosalind plugins you used to make it happen!
Joy Jiao retweeted
At OpenAI, it's felt like our researchers & engineers have been living in the future with Codex.
Today, we're bringing that same experience to life science researchers with the Rosalind Workbench.
excited to introduce Rosalind Workbench for biologists, built directly into Codex! many more exciting things coming soon :)
developers.openai.com/blog/r…
Joy Jiao retweeted
OpenAI for helping families facing rare genetic diseases. This was done with o3 which is over a year old, amazing to think what will be possible with today’s models.
For families facing rare genetic diseases, answers can be hard to find.
@HallieJackson spoke live with @_perloj and Dr. Catherine Brownstein about the new NEJM AI paper and our work with Boston Children’s Hospital, where experts used o3 Deep Research to help diagnose rare genetic diseases affecting children.
Take a look:
incredibly inspiring work @suyashss and team! this is why we work at openai
excited to measure and improve the helpfulness of our models on high coverage, realistic, and sophisticated biology tasks
we'll be hosting LifeSciBench and other benchmarks on a third party site in the coming months so users can transparently compare model performance
Introducing LifeSciBench, a benchmark for measuring and improving how well AI supports real-world life science research.
Developed with 173 scientists from biotechnology and pharmaceutical research, LifeSciBench includes 750 expert-authored tasks across seven biological research workflows.
openai.com/index/introducing…
one intuition behind 'realistic' prompts and rubrics: when a scientist asks the model to design an experiment, a good design should come with positive and negative controls without the user's explicit prompting. scientists are busy and prompting takes time :)
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Joy Jiao retweeted
Major upgrade to GPT-Rosalind, with much better intelligence for drug discovery, analysis, design, and experimental workflows:
We’re bringing new capabilities to GPT-Rosalind, a model series purpose-built for life sciences research at enterprise scale.
It brings GPT-5.5’s agentic coding and tool use together with stronger intelligence for drug discovery, analysis, design, and experimental workflows.
openai.com/index/introducing…
congrats to the team, especially excited for the new medchem capabilities and performance on our new out of distribution evals! @bacchuswng @yunyunash @suyashss @davediego @edwardzhou_ @kevinrao99
We’re bringing new capabilities to GPT-Rosalind, a model series purpose-built for life sciences research at enterprise scale.
It brings GPT-5.5’s agentic coding and tool use together with stronger intelligence for drug discovery, analysis, design, and experimental workflows.
openai.com/index/introducing…
Next Wednesday at the @OpenAI Forum, I’ll be joined by @perturbai_tx to talk about decoding biological intelligence with AI. GPT-Rosalind is an exciting lead-in to that discussion, and we’re especially excited about the data and the collaboration behind! forum.openai.com/public/even…
















