Chief Scientist | President/Director, https://xitter.twitterapi.xyz/t.co/J0UaHbfGEo | 11,716 biomedical ideas | ICMR (Govt of India, Delhi) Additional Director interview invitee
India
Joined December 2013
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The major medical advances throughout history msn.com/en-in/health/other/t…
The best COVID-19 mechanism of action:1-470. Click on "show replies" to see all. ->Liked by @HarvardCyber
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@ICMRDELHI @IGIBSocial @aiims_newdelhi @NMC_IND @NobelPrize @NIH @WHO @exosome
284/287 Vitamin D3 inhibits Aryl Hydrocarbon Receptor & stalls the progression of COVID-19
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science.org/doi/10.1126/scia…
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Patients with chronic obstructive asthma (COA) develop airflow obstruction caused by subepithelial fibrosis.
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How does p53/NRF2-based therapy protect against airflow obstruction caused by subepithelial fibrosis in patients with chronic obstructive asthma (COA)?
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Abnormal ADAM17 expression causes airway fibrosis in chronic obstructive asthma—PubMed
pubmed.ncbi.nlm.nih.gov/3405…
--
This therapy activates p53 and NRF2 signaling pathways, which help reduce oxidative stress and inflammation. By modulating these pathways, it can decrease fibroblast proliferation and extracellular matrix deposition, ultimately limiting subepithelial fibrosis and improving airflow in COA patients.
---
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The major medical advances throughout history msn.com/en-in/health/other/t…
The best COVID-19 mechanism of action:1-470. Click on "show replies" to see all. ->Liked by @HarvardCyber
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6
How does p53/NRF2-based therapy protect against COVID-19-associated coagulopathy?
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Peripheral blood mononuclear cell tissue factor (F3 gene) transcript levels and circulating extracellular vesicles are elevated in severe coronavirus 2019 (COVID-19) disease—PubMed
pubmed.ncbi.nlm.nih.gov/3669…
Tissue factor in COVID-19-associated coagulopathy—PubMed
pubmed.ncbi.nlm.nih.gov/3626…
Tissue factor upregulation is associated with SARS-CoV-2 in the lungs of COVID-19 patients - PubMed
pubmed.ncbi.nlm.nih.gov/3423…
--
- Proinflammatory cytokines are markedly elevated in COVID-19.
- Key cytokines include IL-1β, IL-6, and TNF-α.
- These cytokines induce tissue factor (TF) expression on immune cells (monocytes, macrophages).
- TF expression is also induced on non-immune cells (endothelial and epithelial cells).
- Similar induction occurs in other inflammatory conditions
---
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@karolinskainst
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--- Nobel winners:
@RiceLaboratory
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@gary_ruvkun
@barjammar
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The major medical advances throughout history msn.com/en-in/health/other/t…
The best COVID-19 mechanism of action:1-470. Click on "show replies" to see all. ->Liked by @HarvardCyber
xitter.twitterapi.xyz/DrLBoominathan/status/…
@ICMRDELHI @IGIBSocial @aiims_newdelhi @NMC_IND @NobelPrize @NIH @WHO @exosome
How might p53/NRF2-based therapy mitigate neuropsychiatric sequelae in post-COVID syndrome patients?
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Neuropsychiatric sequelae in an experimental model of post-COVID syndrome in mice—PubMed
pubmed.ncbi.nlm.nih.gov/4012…
Increasing Nrf2 Activity as a Treatment Approach in Neuropsychiatry - PubMed
pubmed.ncbi.nlm.nih.gov/3341…
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Specifically, how modulation of the p53 and NRF2 pathways may influence neuroinflammation, oxidative stress, and neuronal resilience could provide critical insights into developing targeted treatments for cognitive, emotional, and behavioral impairments observed in post-COVID patients. Further preclinical and clinical studies are warranted to evaluate efficacy, optimal dosing strategies, and long-term outcomes of such therapeutic approaches.
---
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@slinnarsson
@HarrietWallberg
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@karolinskainst
@exosome
@NobelPeaceOslo
@DrNKalaiselvi
@RajivBahl04
--- Nobel winners:
@RiceLaboratory
@AzizGwenSancar
@carol_greider
@gary_ruvkun
@barjammar
@gacd_media
@k_satyarthi
@gary_ruvkun
@kkariko
@WeissmanLab
@kaelin_lab
@RiceLaboratory
@MayBrittMoser
@ardemp
@barjammar
@CarolynBertozzi
@francesarnold
@demishassabis
@dmac68
@madurai_aiims
@OfficialJipmer
The major medical advances throughout history msn.com/en-in/health/other/t…
The best COVID-19 mechanism of action:1-470. Click on "show replies" to see all. ->Liked by @HarvardCyber
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@ICMRDELHI @IGIBSocial @aiims_newdelhi @NMC_IND @NobelPrize @NIH @WHO @exosome
Let us not wait for a single day to honor education; instead, let us embrace every day and every moment as an opportunity to learn and grow, gaining the knowledge that empowers us to be our best.
— Dr. L. Boominathan, PhD, President-Director, GBMD, Genomediscovery.org
@ugc_india @EduMinOfIndia @JoshiPralhad @UNESCO @GreatestQuotes
On the occasion of National Education Day, the Department of Legal Affairs, Ministry of Law and Justice, reaffirms the transformative power of education in shaping informed, responsible and empowered citizens.
#NationalEducationDay
#RightToEducation
(1/2)
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How does p53/NRF2-based therapy protect against pulmonary emphysema in covid-19 patients?
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ADAM17 Deficiency Protects against Pulmonary Emphysema—PubMed
pubmed.ncbi.nlm.nih.gov/3318…
Pulmonary emphysema, bullae, and pneumothorax in COVID-19 pneumonia - PubMed
pubmed.ncbi.nlm.nih.gov/3355…
--
How can p53/NRF2-based therapy help safeguard the lungs of COVID-19 patients suffering from pulmonary emphysema and potentially improve their breathing and overall quality of life?
---
@ICMRDELHI
@NMC_BHARAT
@NITIAayog
@HarvardCyber
@evp_iisc
@iitmadras
-- Members of the noble assembly:
@NobelPrize
@JuleenRZierath
@perlmannlab
@slinnarsson
@HarrietWallberg
--
@karolinskainst
@exosome
@NobelPeaceOslo
@DrNKalaiselvi
@RajivBahl04
--- Nobel winners:
@RiceLaboratory
@AzizGwenSancar
@carol_greider
@gary_ruvkun
@barjammar
@gacd_media
@k_satyarthi
@gary_ruvkun
@kkariko
@WeissmanLab
@kaelin_lab
@RiceLaboratory
@MayBrittMoser
@ardemp
@barjammar
@CarolynBertozzi
@francesarnold
@demishassabis
@dmac68 @madurai_aiims @OfficialJipmer
The major medical advances throughout history msn.com/en-in/health/other/t…
The best COVID-19 mechanism of action:1-470. Click on "show replies" to see all. ->Liked by @HarvardCyber
xitter.twitterapi.xyz/DrLBoominathan/status/…
@ICMRDELHI @IGIBSocial @aiims_newdelhi @NMC_IND @NobelPrize @NIH @WHO @exosome
1
19
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@ct_bergstrom
@BallouxFrancois
@EricTopol
5
How does p53/NRF2-based therapy protect against pulmonary emphysema in covid-19 patients?
--
ADAM17 Deficiency Protects against Pulmonary Emphysema—PubMed
pubmed.ncbi.nlm.nih.gov/3318…
Pulmonary emphysema, bullae, and pneumothorax in COVID-19 pneumonia - PubMed
pubmed.ncbi.nlm.nih.gov/3355…
--
How can p53/NRF2-based therapy help safeguard the lungs of COVID-19 patients suffering from pulmonary emphysema and potentially improve their breathing and overall quality of life?
---
@ICMRDELHI
@NMC_BHARAT
@NITIAayog
@HarvardCyber
@evp_iisc
@iitmadras
-- Members of the noble assembly:
@NobelPrize
@JuleenRZierath
@perlmannlab
@slinnarsson
@HarrietWallberg
--
@karolinskainst
@exosome
@NobelPeaceOslo
@DrNKalaiselvi
@RajivBahl04
--- Nobel winners:
@RiceLaboratory
@AzizGwenSancar
@carol_greider
@gary_ruvkun
@barjammar
@gacd_media
@k_satyarthi
@gary_ruvkun
@kkariko
@WeissmanLab
@kaelin_lab
@RiceLaboratory
@MayBrittMoser
@ardemp
@barjammar
@CarolynBertozzi
@francesarnold
@demishassabis
@dmac68 @madurai_aiims @OfficialJipmer
The major medical advances throughout history msn.com/en-in/health/other/t…
The best COVID-19 mechanism of action:1-470. Click on "show replies" to see all. ->Liked by @HarvardCyber
xitter.twitterapi.xyz/DrLBoominathan/status/…
@ICMRDELHI @IGIBSocial @aiims_newdelhi @NMC_IND @NobelPrize @NIH @WHO @exosome
6
How does p53/NRF2-based therapy protect against pulmonary emphysema in covid-19 patients?
--
ADAM17 Deficiency Protects against Pulmonary Emphysema—PubMed
pubmed.ncbi.nlm.nih.gov/3318…
Pulmonary emphysema, bullae, and pneumothorax in COVID-19 pneumonia - PubMed
pubmed.ncbi.nlm.nih.gov/3355…
--
How can p53/NRF2-based therapy help safeguard the lungs of COVID-19 patients suffering from pulmonary emphysema and potentially improve their breathing and overall quality of life?
---
@ICMRDELHI
@NMC_BHARAT
@NITIAayog
@HarvardCyber
@evp_iisc
@iitmadras
-- Members of the noble assembly:
@NobelPrize
@JuleenRZierath
@perlmannlab
@slinnarsson
@HarrietWallberg
--
@karolinskainst
@exosome
@NobelPeaceOslo
@DrNKalaiselvi
@RajivBahl04
--- Nobel winners:
@RiceLaboratory
@AzizGwenSancar
@carol_greider
@gary_ruvkun
@barjammar
@gacd_media
@k_satyarthi
@gary_ruvkun
@kkariko
@WeissmanLab
@kaelin_lab
@RiceLaboratory
@MayBrittMoser
@ardemp
@barjammar
@CarolynBertozzi
@francesarnold
@demishassabis
@dmac68 @madurai_aiims @OfficialJipmer
The major medical advances throughout history msn.com/en-in/health/other/t…
The best COVID-19 mechanism of action:1-470. Click on "show replies" to see all. ->Liked by @HarvardCyber
xitter.twitterapi.xyz/DrLBoominathan/status/…
@ICMRDELHI @IGIBSocial @aiims_newdelhi @NMC_IND @NobelPrize @NIH @WHO @exosome
11
How does p53/NRF2-based therapy protect against pulmonary emphysema in covid-19 patients?
--
ADAM17 Deficiency Protects against Pulmonary Emphysema—PubMed
pubmed.ncbi.nlm.nih.gov/3318…
Pulmonary emphysema, bullae, and pneumothorax in COVID-19 pneumonia - PubMed
pubmed.ncbi.nlm.nih.gov/3355…
--
How can p53/NRF2-based therapy help safeguard the lungs of COVID-19 patients suffering from pulmonary emphysema and potentially improve their breathing and overall quality of life?
---
@ICMRDELHI
@NMC_BHARAT
@NITIAayog
@HarvardCyber
@evp_iisc
@iitmadras
-- Members of the noble assembly:
@NobelPrize
@JuleenRZierath
@perlmannlab
@slinnarsson
@HarrietWallberg
--
@karolinskainst
@exosome
@NobelPeaceOslo
@DrNKalaiselvi
@RajivBahl04
--- Nobel winners:
@RiceLaboratory
@AzizGwenSancar
@carol_greider
@gary_ruvkun
@barjammar
@gacd_media
@k_satyarthi
@gary_ruvkun
@kkariko
@WeissmanLab
@kaelin_lab
@RiceLaboratory
@MayBrittMoser
@ardemp
@barjammar
@CarolynBertozzi
@francesarnold
@demishassabis
@dmac68 @madurai_aiims @OfficialJipmer
The major medical advances throughout history msn.com/en-in/health/other/t…
The best COVID-19 mechanism of action:1-470. Click on "show replies" to see all. ->Liked by @HarvardCyber
xitter.twitterapi.xyz/DrLBoominathan/status/…
@ICMRDELHI @IGIBSocial @aiims_newdelhi @NMC_IND @NobelPrize @NIH @WHO @exosome
7
Dr L Boominathan PhD on X: "🌍 International Week of Science and Peace 2026: The Discovery Humanity Never Counts" / X
xitter.twitterapi.xyz/DrLBoominathan/status/…
--
@UNESCO @ugc_india
--- Nobel winners:
@RiceLaboratory
@AzizGwenSancar
@carol_greider
@gary_ruvkun
@barjammar
@gacd_media
@k_satyarthi
@gary_ruvkun
@kkariko
@WeissmanLab
@kaelin_lab
@RiceLaboratory
@MayBrittMoser
@ardemp
@barjammar
@CarolynBertozzi
@francesarnold
@demishassabis
@dmac68
@CovidIndiaSeva
Science must be accessible to everyone, everywhere.
This #WorldScienceDay, Prof. Rajaâ Cherkaoui El Moursli, a nuclear physicist and jury member of the @UNESCO-Equatorial Guinea International Prize reminds us: recognising scientific excellence wherever it emerges is key to building a more inclusive scientific community.
Learn more: unesco.org/en/days/science-p…
#ScienceForAll #ForThePeople
1
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@PHAssociation
@long_covid
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@PlzSolveCFS
@LongCovidKids
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@LongCOVIDPhysio
@TreatLongCovid
@LongCovidAdvoc
@polybioRF
@longcovidfdn
@longcovidanswer
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@ct_bergstrom
@BallouxFrancois
@EricTopol
9
Major medical institutions and Health ministries:
@ICMRDELHI
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@nimr_delhi
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Air pollution shares several mechanistic similarities with COVID-19. Many of the genes activated by SARS-CoV-2, including TLR4, are also triggered by air pollution, which can contribute to cognitive impairment, among other effects.
This overlap suggests that interventions targeting inflammatory pathways like TLR4 could potentially mitigate the health impacts of both viral infections and environmental pollutants. Understanding these shared mechanisms underscores the need for urgent, science-based public health strategies to reduce air pollution exposure.
--
SARS-CoV-2 causes senescence in human cells and exacerbates the senescence-associated secretory phenotype through TLR-3 - PubMed
pubmed.ncbi.nlm.nih.gov/3453…
PM2.5 increases mouse blood pressure by activating toll-like receptor 3 - PubMed
pubmed.ncbi.nlm.nih.gov/3524…
--
PM2.5 exposure upregulates pro-inflammatory protein expression in human microglial cells via oxidant stress and TLR4/NF-κB pathway - PubMed
pubmed.ncbi.nlm.nih.gov/3865…
SARS-CoV-2 Spike protein induces TLR4-mediated long-term cognitive dysfunction recapitulating post-COVID-19 syndrome in mice - PubMed
--
@narendramodi ji @DrLBoominathan @PMOIndia @rashtrapatibhvn
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-- Members of the noble assembly:
@NobelPrize
@JuleenRZierath
@perlmannlab
@slinnarsson
@HarrietWallberg
--
@karolinskainst
@exosome
@NobelPeaceOslo @harpviken
@DrNKalaiselvi
@RajivBahl04 @drmohanv @mansukhmandviya @drkarthik2010 @DrRajsekar @CSIR_IND @NMC_BHARAT @NITIAayog
-----
grok.com/imagine/post/48fa58…
1
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AIIMS:
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@mangalAiimsAP
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1
6
Air pollution shares several mechanistic similarities with COVID-19. Many of the genes activated by SARS-CoV-2, including TLR4, are also triggered by air pollution, which can contribute to cognitive impairment, among other effects.
This overlap suggests that interventions targeting inflammatory pathways like TLR4 could potentially mitigate the health impacts of both viral infections and environmental pollutants. Understanding these shared mechanisms underscores the need for urgent, science-based public health strategies to reduce air pollution exposure.
--
SARS-CoV-2 causes senescence in human cells and exacerbates the senescence-associated secretory phenotype through TLR-3 - PubMed
pubmed.ncbi.nlm.nih.gov/3453…
PM2.5 increases mouse blood pressure by activating toll-like receptor 3 - PubMed
pubmed.ncbi.nlm.nih.gov/3524…
--
PM2.5 exposure upregulates pro-inflammatory protein expression in human microglial cells via oxidant stress and TLR4/NF-κB pathway - PubMed
pubmed.ncbi.nlm.nih.gov/3865…
SARS-CoV-2 Spike protein induces TLR4-mediated long-term cognitive dysfunction recapitulating post-COVID-19 syndrome in mice - PubMed
--
@narendramodi ji @DrLBoominathan @PMOIndia @rashtrapatibhvn
@NMC_IND
@NITIAayog
@antonioguterres
@UN
@DrTedros
@WHO
@exosome
@realDonaldTrump @EmmanuelMacron
@UN
@10DowningStreet
@VP
@CPR_VP
@Punam_Bhargava
@GujScienceCity
@LtGovDelhi
@lokbhavan_tn
@HarvardCyber
-- Members of the noble assembly:
@NobelPrize
@JuleenRZierath
@perlmannlab
@slinnarsson
@HarrietWallberg
--
@karolinskainst
@exosome
@NobelPeaceOslo @harpviken
@DrNKalaiselvi
@RajivBahl04 @drmohanv @mansukhmandviya @drkarthik2010 @DrRajsekar @CSIR_IND @NMC_BHARAT @NITIAayog
-----
grok.com/imagine/post/48fa58…
🤖 Made with AI
My interview with @IndiaToday on why we need a Covid like, all of government, Multi- sectoral urgent action on #AirPollution. Science based, public health oriented action is needed - a Swachh Vayu Abhiyaan. indiatoday.in/health/story/i…
Air pollution is no different from covid mechanism-wise, almost; it is just that most did not know the mechanism of action yet. What genes turned on by covid are almost identical to what get turned on by air pollution, such as TLR4, resulting in cognitive impairment, to name one.
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1
8
How does p53/NRF2-based therapy help prevent breast cancer progression, limit the activation of metastatic breast cancer cells, reduce mutation accumulation, and decrease the emergence of new mutations?
--
Respiratory viral infections awaken metastatic breast cancer cells in lungs—PubMed
pubmed.ncbi.nlm.nih.gov/4073…
nature.com/articles/s41586-0…
APOBEC3B is an enzymatic source of mutation in breast cancer—PubMed.
pubmed.ncbi.nlm.nih.gov/2338…
doi.org/10.1038/nature11881
--
@ICMRDELHI
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@NITIAayog
@HarvardCyber
@evp_iisc
@iitmadras
-- Members of the noble assembly:
@NobelPrize
@JuleenRZierath
@perlmannlab
@slinnarsson
@HarrietWallberg
--
@karolinskainst
@exosome
@NobelPeaceOslo
@DrNKalaiselvi
@RajivBahl04
--- Nobel winners:
@RiceLaboratory
@AzizGwenSancar
@carol_greider
@gary_ruvkun
@barjammar
@gacd_media
@k_satyarthi
@gary_ruvkun
@kkariko
@WeissmanLab
@kaelin_lab
@RiceLaboratory
@MayBrittMoser
@ardemp
@barjammar
@CarolynBertozzi
@francesarnold
@demishassabis
@dmac68
How does p53/NRF2-based therapy contribute to preventing breast cancer progression, limiting mutation accumulation, and reducing the emergence of new mutations?
--
APOBEC3B is an enzymatic source of mutation in breast cancer—PubMed
pubmed.ncbi.nlm.nih.gov/2338…
doi.org/10.1038/nature11881
--
@ICMRDELHI @NMC_BHARAT @NITIAayog
@HarvardCyber @evp_iisc @iitmadras
-- Members of the noble assembly:
@NobelPrize
@JuleenRZierath
@perlmannlab
@slinnarsson
@HarrietWallberg
--
@karolinskainst
@exosome
@NobelPeaceOslo
@DrNKalaiselvi
@RajivBahl04
--- Nobel winners:
@RiceLaboratory
@AzizGwenSancar
@carol_greider
@gary_ruvkun
@barjammar
@gacd_media
@k_satyarthi
@gary_ruvkun
@kkariko
@WeissmanLab
@kaelin_lab
@RiceLaboratory
@MayBrittMoser
@ardemp
@barjammar
@CarolynBertozzi
@francesarnold
@demishassabis
@dmac68
Aspire to develop a flawless system and become the proudest citizen of democracy.
@CMOTamilnadu @NrCongres
@CmofKarnataka
@TelanganaCMO
@AndhraPradeshCM
@CMOKerala
@CMODelhi
@cmohry
@CMOMaharashtra
@ArunachalCMO
@goacm
@CMOFFICEHP
@moayush
@CMOGuj
@varicose_india
@myogioffice
@CMMadhyaPradesh
@CMofKarnataka
@cmohry
@JharkhandCMO
@DrLavina_IPS
@jayantmuraliips
@Venkatesham_IPS
@drvishal_singh
@niharika_bhatt
@IPS_Association
@IASassociation
@IMAMSNMP
Humanity measures publications, patents, and prizes. It rarely measures the discoveries that never occurred because productive scientific time was lost.
Now published:
Accountability Infrastructure and Scientific Opportunity Loss: A Framework for Protecting Scientific Time, Institutional Trust and Human Progress
DOI: doi.org/10.5281/zenodo.24097…
#Science #Innovation #Governance #CLEARBOOMI #NOWAR #ScientificOpportunityLoss #Peace #Development #WorldScienceDay 🧬
🌍⚖️
Video link: share.gemini.google/YZezk3Mc…
--
@narendramodi ji @DrLBoominathan @PMOIndia @rashtrapatibhvn
@NMC_IND
@NITIAayog
@antonioguterres
@UN
@DrTedros
@WHO
@exosome
@realDonaldTrump @EmmanuelMacron
@UN
@10DowningStreet
@VP
@CPR_VP
@Punam_Bhargava
@GujScienceCity
@LtGovDelhi
@lokbhavan_tn
@HarvardCyber
-- Members of the noble assembly:
@NobelPrize
@JuleenRZierath
@perlmannlab
@slinnarsson
@HarrietWallberg
--
@karolinskainst
@exosome
@NobelPeaceOslo
@DrNKalaiselvi
@RajivBahl04
grok.com/imagine/post/c7b4ff…
grok.com/imagine/post/ef585f…
1
9
Strive to create an exemplary system and take pride in being a model citizen of a true democracy
@governorap
@GovParnaik
@AssamRajbhavan
@GovernorBihar
@GovernorCG
@ADevvrat
@RajBhavanHry
@RajBhavanHP
@LokBhavanJandK
@jhar_governor
@GovernorofKar
@KeralaGovernor
@GovernorMP
@maha_governor
@RajBhavManipur
@MeghalayaGov
@MizoramGovernor
@RajBhavanKohima
@GovernorOdisha
@LGov_Puducherry
@Gulab_kataria
@RajBhavanJaipur
@TripuraGovernor
@UttarakhandRB
@GovernorofUp
@BengalGovernor
@lokbhavan_wb
@lokbhavan_tn
5
Humanity measures publications, patents, and prizes. It rarely measures the discoveries that never occurred because productive scientific time was lost.
Now published:
Accountability Infrastructure and Scientific Opportunity Loss: A Framework for Protecting Scientific Time, Institutional Trust and Human Progress
DOI: doi.org/10.5281/zenodo.24097…
#Science #Innovation #Governance #CLEARBOOMI #NOWAR #ScientificOpportunityLoss #Peace #Development #WorldScienceDay 🧬
🌍⚖️
Video link: share.gemini.google/YZezk3Mc…
--
@narendramodi ji @DrLBoominathan @PMOIndia @rashtrapatibhvn
@NMC_IND
@NITIAayog
@antonioguterres
@UN
@DrTedros
@WHO
@exosome
@realDonaldTrump @EmmanuelMacron
@UN
@10DowningStreet
@VP
@CPR_VP
@Punam_Bhargava
@GujScienceCity
@LtGovDelhi
@lokbhavan_tn
@HarvardCyber
-- Members of the noble assembly:
@NobelPrize
@JuleenRZierath
@perlmannlab
@slinnarsson
@HarrietWallberg
--
@karolinskainst
@exosome
@NobelPeaceOslo
@DrNKalaiselvi
@RajivBahl04
grok.com/imagine/post/c7b4ff…
grok.com/imagine/post/ef585f…
10
The Nobel Prize
@NobelPrize
·
9m
”The possibilities are endless and I’m excited about what will happen in the future both with fundamental research and with the applications that will solve real world problems in human health and in the environment.” - 2020 chemistry laureate Jennifer Doudna. #ScienceDay
How are clinical trials shaping the future of HR-positive, HER2-negative mBC? In the final episode of Breast Cancer Dialogues, Azadeh Nasrazadani and Filipa Lynce discuss challenges and consider how ongoing research may help improve outcomes for patients in the future
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By defending a fool, you risk becoming one yourself; by defending a criminal, you align with wrongdoing; and by defending no one, you remain insignificant. Stand with those of integrity to become someone of true value rather than a wasted opportunity.
--Dr. Boominathan, PhD
@GreatestQuotes @motivational
8
NAC (N-acetyl cysteine) -> induces miR141 -> decreases keap1 -> increases nrf2 -> decreases CXCL1-CXCR2 signaling:
--
miR141-CXCL1-CXCR2 signaling-induced Treg recruitment regulates metastases and survival of non-small cell lung cancer—PubMed
pubmed.ncbi.nlm.nih.gov/2534…
@exosome @ICMRDELHI @iiscbangalore
Metformin can increase natural killer cell cytotoxicity in head and neck cancer. Clinical and laboratory studies identified enhanced NK-cell activity through CXCL1 inhibition and STAT1 signaling, suggesting an unexpected immunological mechanism for this diabetes medication. jitc.bmj.com/content/10/11/e…
